IUPAC/Chemical Name
(((3R,3aS,6aR,9aR,9bS)-6,9-Dimethylene-2-oxododecahydroazuleno[4,5-b]furan-3-yl)methyl)-L-asparagine
InChi Key
MZFVEYVQALPRDY-HHHJXDIYSA-N
InChi Code
InChI=1S/C19H26N2O5/c1-9-3-6-12-13(8-21-14(18(23)24)7-15(20)22)19(25)26-17(12)16-10(2)4-5-11(9)16/h11-14,16-17,21H,1-8H2,(H2,20,22)(H,23,24)/t11-,12-,13-,14-,16-,17-/m0/s1
SMILES Code
O=C(N)C[C@@H](C(O)=O)NC[C@H]1[C@@](CC2)([H])[C@]([C@@]3([H])C(CC[C@@]3([H])C2=C)=C)([H])OC1=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
362.43
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Chen KB, Chen KC, Chang YL, Chang KL, Chang PC, Chang TT, Chen YC. In Silico Investigation of Traditional Chinese Medicine for Potential Lead Compounds as SPG7 Inhibitors against Coronary Artery Disease. Molecules. 2016 May 5;21(5). pii: E588. doi: 10.3390/molecules21050588. PubMed PMID: 27164068; PubMed Central PMCID: PMC6273800.
2: Tou WI, Chang KL, Chang TT, Lee CC, Chen CY. Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants. J Mol Model. 2016 Jan;22(1):4. doi: 10.1007/s00894-015-2875-y. Epub 2015 Dec 8. PubMed PMID: 26645808.
3: Chen KC, Lee WY, Chen HY, Chen CY. In silico investigation of potential TRAF6 inhibitor from traditional Chinese medicine against cancers. Biomed Res Int. 2014;2014:429486. doi: 10.1155/2014/429486. Epub 2014 Jun 25. PubMed PMID: 25089269; PubMed Central PMCID: PMC4096009.
4: Chen KC, Chen KB, Chen HY, Chen CY. In silico investigation of potential pyruvate kinase M2 regulators from traditional Chinese medicine against cancers. Biomed Res Int. 2014;2014:189495. doi: 10.1155/2014/189495. Epub 2014 Jun 25. PubMed PMID: 25089263; PubMed Central PMCID: PMC4096393.
5: Hung TC, Chen KB, Lee WY, Chen CY. The inhibition of folylpolyglutamate synthetase (folC) in the prevention of drug resistance in Mycobacterium tuberculosis by traditional Chinese medicine. Biomed Res Int. 2014;2014:635152. doi: 10.1155/2014/635152. Epub 2014 Jun 19. PubMed PMID: 25050369; PubMed Central PMCID: PMC4090511.
6: Hung TC, Lee WY, Chen KB, Chan YC, Chen CY. Insight into HIV of IFN-induced myxovirus resistance 2 (MX2) expressed by traditional Chinese medicine. Biomed Res Int. 2014;2014:871576. doi: 10.1155/2014/871576. Epub 2014 Jun 18. PubMed PMID: 25045710; PubMed Central PMCID: PMC4086518.
7: Hung TC, Lee WY, Chen KB, Chan YC, Chen CY. An investigation of small GTPases in relation to liver tumorigenesis using traditional Chinese medicine. Biomed Res Int. 2014;2014:428210. doi: 10.1155/2014/428210. Epub 2014 Jun 19. PubMed PMID: 25045674; PubMed Central PMCID: PMC4090509.
8: Hung TC, Lee WY, Chen KB, Chen CY. Lead screening for CXCR4 of the human HIV infection receptor inhibited by traditional Chinese medicine. Biomed Res Int. 2014;2014:809816. doi: 10.1155/2014/809816. Epub 2014 Jun 5. PubMed PMID: 24999477; PubMed Central PMCID: PMC4066726.
9: Hung TC, Chen KB, Huang HJ, Chen CY. Lead Screening for HIV of C-C Chemokine Receptor Type 5 Receptor Inhibited by Traditional Chinese Medicine. Evid Based Complement Alternat Med. 2014;2014:313094. doi: 10.1155/2014/313094. Epub 2014 Apr 30. PubMed PMID: 24876870; PubMed Central PMCID: PMC4021832.
