MedKoo Cat#: 555412 | Name: cvxIAA
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

cvxIAA is an orthogonal auxin-TIR1 receptor pair. cvxIAA triggers auxin signaling without interfering with endogenous auxin or TIR1/AFBs. cvxIAA hijacked the downstream auxin signaling in vivo both at the transcriptomic level and in specific developmental contexts, only in the presence of a complementary, concave TIR1 (ccvTIR1) receptor. cvxIAA-ccvTIR1 system serves as a powerful tool for solving outstanding questions in auxin biology and for precise manipulation of auxin-mediated processes as a controllable switch.

Chemical Structure

cvxIAA
cvxIAA
CAS#2127037-35-6

Theoretical Analysis

MedKoo Cat#: 555412

Name: cvxIAA

CAS#: 2127037-35-6

Chemical Formula: C17H15NO3

Exact Mass: 281.1052

Molecular Weight: 281.31

Elemental Analysis: C, 72.58; H, 5.37; N, 4.98; O, 17.06

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
50mg USD 1,250.00 2 Weeks
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Related CAS #
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Synonym
cvxIAA; convex IAA; 5-(3-MeOPh)-IAA;
IUPAC/Chemical Name
5-(3-Methoxyphenyl)indole-3-acetic Acid
InChi Key
QVAIVXZPAOBKHG-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H15NO3/c1-21-14-4-2-3-11(7-14)12-5-6-16-15(8-12)13(10-18-16)9-17(19)20/h2-8,10,18H,9H2,1H3,(H,19,20)
SMILES Code
O=C(O)CC1=CNC2=C1C=C(C3=CC=CC(OC)=C3)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 281.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yamada R, Murai K, Uchida N, Takahashi K, Iwasaki R, Tada Y, Kinoshita T, Itami K, Torii KU, Hagihara S. A Super Strong Engineered Auxin-TIR1 Pair. Plant Cell Physiol. 2018 Aug 1;59(8):1538-1544. doi: 10.1093/pcp/pcy127. PubMed PMID: 29986114; PubMed Central PMCID: PMC6084576. 2: Uchida N, Takahashi K, Iwasaki R, Yamada R, Yoshimura M, Endo TA, Kimura S, Zhang H, Nomoto M, Tada Y, Kinoshita T, Itami K, Hagihara S, Torii KU. Chemical hijacking of auxin signaling with an engineered auxin-TIR1 pair. Nat Chem Biol. 2018 Mar;14(3):299-305. doi: 10.1038/nchembio.2555. Epub 2018 Jan 22. PubMed PMID: 29355850; PubMed Central PMCID: PMC5812785.