AS 183 | CAS# 147317-12-2 | Cholesterol Acyltransferase Inhibitor

MedKoo Cat#: 573292 | Name: AS 183

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).

Chemical Structure

AS 183

CAS#147317-12-2

Theoretical Analysis

MedKoo Cat#: 573292

Name: AS 183

CAS#: 147317-12-2

Chemical Formula: C19H34O3

Exact Mass: 310.2508

Molecular Weight: 310.48

Elemental Analysis: C, 73.50; H, 11.04; O, 15.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AS 183, AS-183, AS183

IUPAC/Chemical Name

3(2H)-Furanone, 2-hydroxy-2,4-dimethyl-5-(1,3,5,7-tetramethylnonyl)-

InChi Key

DVCQIWCKLKWXEA-UHFFFAOYSA-N

InChi Code

1S/C19H34O3/c1-8-12(2)9-13(3)10-14(4)11-15(5)17-16(6)18(20)19(7,21)22-17/h12-15,21H,8-11H2,1-7H3

SMILES Code

O=C1C(C)(O)OC(C(C)CC(C)CC(C)CC(C)CC)=C1C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 310.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kuroda K, Yoshida M, Uosaki Y, Ando K, Kawamoto I, Oishi E, Onuma H, Yamada K, Matsuda Y. AS-183, a novel inhibitor of acyl-CoA: cholesterol acyltransferase produced by Scedosporium sp. SPC-15549. J Antibiot (Tokyo). 1993 Aug;46(8):1196-202. PubMed PMID: 8407580.