MedKoo Cat#: 573287 | Name: Aseanostatin P5
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aseanostatin P5 is a cytotoxic polyketide isolated from marine-derived Streptomyces species, belonging to a family of compounds known for their complex macrolide-like structures. It exhibits anticancer bioactivity, particularly through inhibition of tumor cell proliferation in vitro, although its exact molecular target and mechanism of action remain under investigation. Structurally related to other aseanostatins, it is part of ongoing research into marine natural products as sources of novel chemotherapeutic agents.

Chemical Structure

Aseanostatin P5
Aseanostatin P5
CAS#5502-94-3

Theoretical Analysis

MedKoo Cat#: 573287

Name: Aseanostatin P5

CAS#: 5502-94-3

Chemical Formula: C15H30O2

Exact Mass: 242.2246

Molecular Weight: 242.40

Elemental Analysis: C, 74.32; H, 12.48; O, 13.20

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
10mg USD 700.00 2 Weeks
25mg USD 1,050.00 2 Weeks
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Related CAS #
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Synonym
12-Methyltetradecanoic acid; Aseanostatin P5; Sarcinic acid; FA 15:0; (±)-12-methyl Tetradecanoic Acid
IUPAC/Chemical Name
Tetradecanoic acid, 12-methyl-
InChi Key
XKLJLHAPJBUBNL-UHFFFAOYSA-N
InChi Code
1S/C15H30O2/c1-3-14(2)12-10-8-6-4-5-7-9-11-13-15(16)17/h14H,3-13H2,1-2H3,(H,16,17)
SMILES Code
C([C@@H](CC)C)CCCCCCCCCC(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 242.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Impact on lipid membrane organization by free branched-chain fatty acids. Phys Chem Chem Phys. 2006 Nov 7;8(41):4792-7. doi: 10.1039/b607460j. Epub 2006 Sep 19. PMID: 17043723. 12: Colnaghi Simionato AV, da Silva DS, Lambais MR, Carrilho E. Characterization of a putative Xylella fastidiosa diffusible signal factor by HRGC-EI-MS. J Mass Spectrom. 2007 Apr;42(4):490-6. doi: 10.1002/jms.1181. PMID: 17295415. 13: Xu Y, Li H, Li X, Xiao X, Qian PY. Inhibitory effects of a branched-chain fatty acid on larval settlement of the polychaete Hydroides elegans. Mar Biotechnol (NY). 2009 Jul-Aug;11(4):495-504. doi: 10.1007/s10126-008-9161-2. Epub 2008 Nov 22. PMID: 19030931. 14: Cole N, Hume EB, Jalbert I, Vijay AK, Krishnan R, Willcox MD. Effects of topical administration of 12-methyl tetradecanoic acid (12-MTA) on the development of corneal angiogenesis. Angiogenesis. 2007;10(1):47-54. doi: 10.1007/s10456-007-9063-3. Epub 2007 Feb 13. PMID: 17295090. 15: HANSEN RP, SHORLAND FB, COOKE NJ. The branched-chain fatty acids of butterfat. IV. The isolation of (+)-12-methyltetradecanoic acid and of 13-methyltetradecanoic acid. Biochem J. 1954 Jun;57(2):297-301. doi: 10.1042/bj0570297. PMID: 13172183; PMCID: PMC1269745. 16: Inoue T, Kuroda T, Ohara N. 12-Methyltetradecanoic acid, a branched-chain fatty acid, represses the extracellular production of surfactants required for swarming motility in Pseudomonas aeruginosa PAO1. Jpn J Infect Dis. 2012;65(2):126-31. PMID: 22446119. 17: Edgcomb MR, Sirimanne S, Wilkinson BJ, Drouin P, Morse RD. Electron paramagnetic resonance studies of the membrane fluidity of the foodborne pathogenic psychrotroph Listeria monocytogenes. Biochim Biophys Acta. 2000 Jan 15;1463(1):31-42. doi: 10.1016/s0005-2736(99)00179-0. PMID: 10631292. 18: HANSEN RP, SHORLAND FB, COOKE NJ. The branched-chain fatty acids of mutton fat. II. The isolation of (+)-12-methyltetradecanoic acid and the 13-methyltetradecanoic acid. Biochem J. 1953 Feb;53(3):374-8. doi: 10.1042/bj0530374. PMID: 13032080; PMCID: PMC1198159. 19: Yang P, Collin P, Madden T, Chan D, Sweeney-Gotsch B, McConkey D, Newman RA. Inhibition of proliferation of PC3 cells by the branched-chain fatty acid, 12-methyltetradecanoic acid, is associated with inhibition of 5-lipoxygenase. Prostate. 2003 Jun 1;55(4):281-91. doi: 10.1002/pros.10243. PMID: 12712407. 20: Ramm W, Schatton W, Wagner-Döbler I, Wray V, Nimtz M, Tokuda H, Enjyo F, Nishino H, Beil W, Heckmann R, Lurtz V, Lang S. Diglucosyl-glycerolipids from the marine sponge-associated Bacillus pumilus strain AAS3: their production, enzymatic modification and properties. Appl Microbiol Biotechnol. 2004 May;64(4):497-504. doi: 10.1007/s00253-003-1471-8. Epub 2003 Oct 31. PMID: 14593508.