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MedKoo Cat#: 471016 | Name: LUF6283
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

LUF6283 is a partial agonist of hydroxycarboxylic acid receptor 2

Chemical Structure

LUF6283
LUF6283
CAS#92933-48-7

Theoretical Analysis

MedKoo Cat#: 471016

Name: LUF6283

CAS#: 92933-48-7

Chemical Formula: C8H12N2O2

Exact Mass: 168.0899

Molecular Weight: 168.20

Elemental Analysis: C, 57.13; H, 7.19; N, 16.66; O, 19.02

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 weeks
50mg USD 750.00 2 weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
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Related CAS #
No Data
Synonym
LUF6283, LUF-6283, LUF 6283
IUPAC/Chemical Name
5-butyl-1H-pyrazole-3-carboxylic acid
InChi Key
ZJTXSGLJNBAMJS-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H12N2O2/c1-2-3-4-6-5-7(8(11)12)10-9-6/h5H,2-4H2,1H3,(H,9,10)(H,11,12)
SMILES Code
O=C(C1=NNC(CCCC)=C1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
LUF6283 is a potent and orally active HCA(2) partial agonist, with a Ki of 0.55 µM.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMSO 16.0 95.13
Ethanol 16.0 95.13
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 168.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1. Li, Z., Blad, C.C., van der Sluis, R.J., et al. Effects of pyrazole partial agonists on HCA2-mediated flushing and VLDL-triglyceride levels in mice Br. J. Pharmacol. 167(4), 818-825 (2012).