MedKoo Cat#: 573251 | Name: Ticagrelor metabolite M5
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ticagrelor metabolite M5, also known as AR-C133913XX, is a metabolite of Ticagrelor which is the first reversible oral P2Y12 receptor antagonist. Ticagrelor provides faster and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).

Chemical Structure

Ticagrelor metabolite M5
Ticagrelor metabolite M5
CAS#1251765-07-7

Theoretical Analysis

MedKoo Cat#: 573251

Name: Ticagrelor metabolite M5

CAS#: 1251765-07-7

Chemical Formula: C14H22N6O4S

Exact Mass: 370.1423

Molecular Weight: 370.43

Elemental Analysis: C, 45.39; H, 5.99; N, 22.69; O, 17.28; S, 8.65

Price and Availability

Size Price Availability Quantity
100mg USD 500.00 2 weeks
250mg USD 850.00 2 weeks
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Related CAS #
No Data
Synonym
AR-C133913XX, T437700, Ticagrelor metabolite M5,
IUPAC/Chemical Name
(1S,2S,3R,5S)-3-(7-Amino-5-propylsulfanyltriazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
InChi Key
YTYBSYIHUFBLKV-YKDSUIRESA-N
InChi Code
1S/C14H22N6O4S/c1-2-5-25-14-16-12(15)9-13(17-14)20(19-18-9)7-6-8(24-4-3-21)11(23)10(7)22/h7-8,10-11,21-23H,2-6H2,1H3,(H2,15,16,17)/t7-,8+,10+,11-/m1/s1
SMILES Code
CCCSc1nc(c2c(n1)n(nn2)[C@@H]3C[C@@H]([C@H]([C@H]3O)O)OCCO)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 370.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Teng R, Oliver S, Hayes MA, Butler K. Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects. Drug Metab Dispos. 2010 Sep;38(9):1514-21. doi: 10.1124/dmd.110.032250. Epub 2010 Jun 15. PMID: 20551239.