MedKoo Cat#: 584742 | Name: Miconidin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Miconidin is found in Primula, a precursor to primin, and inhibits growth in Trypanosoma cruzi.

Chemical Structure

Miconidin
Miconidin
CAS#34272-58-7

Theoretical Analysis

MedKoo Cat#: 584742

Name: Miconidin

CAS#: 34272-58-7

Chemical Formula: C12H18O3

Exact Mass: 210.1256

Molecular Weight: 210.27

Elemental Analysis: C, 68.55; H, 8.63; O, 22.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Miconidin
IUPAC/Chemical Name
1,4-Benzenediol, 2-methoxy-6-pentyl-
InChi Key
QYDCWUURASKCKV-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H18O3/c1-3-4-5-6-9-7-10(13)8-11(15-2)12(9)14/h7-8,13-14H,3-6H2,1-2H3
SMILES Code
OC1=C(CCCCC)C=C(O)C=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 210.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Paulsen E, Christensen LP, Andersen KE. Miconidin and miconidin methyl ether from Primula obconica Hance: new allergens in an old sensitizer. Contact Dermatitis. 2006 Oct;55(4):203-9. PubMed PMID: 16958917. 2: Sepúlveda-Boza S, Cassels BK. Plant metabolites active against Trypanosoma cruzi. Planta Med. 1996 Apr;62(2):98-105. Review. PubMed PMID: 8657759. 3: Krebs M, Christensen LP. 2-methoxy-6-pentyl-1,4-dihydroxybenzene (miconidin) from Primula obconica: a possible allergen? Contact Dermatitis. 1995 Aug;33(2):90-3. PubMed PMID: 8549150. 4: Christensen LP, Larsen E. Direct emission of the allergen primin from intact Primula obconica plants. Contact Dermatitis. 2000 Mar;42(3):149-53. PubMed PMID: 10727165. 5: Na P, Peng S, Zhang Y, Zhong Y. Composition of volatile oil of Primula obconica in Central China. Nat Prod Lett. 2002 Aug;16(4):249-53. PubMed PMID: 12168760. 6: Goijman SG, Turrens JF, Marini-Bettolo GB, Stoppani AO. [Inhibition of growth and macromolecular biosynthesis in Trypanosoma cruzi by natural products. Effects of miconidine and tingenone]. Medicina (B Aires). 1984;44(4):361-70. Spanish. PubMed PMID: 6399926. 7: Maioral MF, Stefanes NM, Bigolin Á, Zatelli GA, Philippus AC, de Barcellos Falkenberg M, Santos-Silva MC. MICONIDINE acetate, a new selective and cytotoxic compound with synergic potential, induces cell cycle arrest and apoptosis in leukemia cells. Invest New Drugs. 2018 Dec 19. doi: 10.1007/s10637-018-0694-6. [Epub ahead of print] PubMed PMID: 30569243.