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2: Yen JH, Keak PY, Wu CL, Chen HJ, Gao WY, Liou JW, Chen YR, Lin LI, Chen PY. Shikonin, a natural naphthoquinone phytochemical, exerts anti-leukemia effects in human CBF-AML cell lines and zebrafish xenograft models. Biomed Pharmacother. 2024 Sep 5;179:117395. doi: 10.1016/j.biopha.2024.117395. Epub ahead of print. PMID: 39241566.
3: Saeed M, Shoaib A, Tasleem M, Al-Shammary A, Kausar MA, El Asmar Z, Abdelgadir A, Sulieman AME, Ahmed EH, Zahin M, Ansari IA. Role of Alkannin in the Therapeutic Targeting of Protein-Tyrosine Phosphatase 1B and Aldose Reductase in Type 2 Diabetes: An In Silico and In Vitro Evaluation. ACS Omega. 2024 Aug 18;9(34):36099-36113. doi: 10.1021/acsomega.4c00082. PMID: 39220541; PMCID: PMC11359625.
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5: Liu W, Zhao Y, Liu Q, Wu D, Li W, Fu Z, Yang L, Liang Y. Systematic bioinformatics analysis reveals the role of shikonin in blocking colon cancer progression by identifying senescence-induced genes. Front Pharmacol. 2024 Aug 12;15:1360587. doi: 10.3389/fphar.2024.1360587. PMID: 39188951; PMCID: PMC11345165.
6: Zeng F, Lai Y, Huang Y, Zhu F, Gao J, Chen Z, Zeng L, Feng M, Qiu P, Yuan S, Deng G. Shikonin from lithospermum erythrorhizon induces pyroptosis in trophoblast cells by activating the CTSB-NLRP3 inflammasome. Ann Med. 2024 Dec;56(1):2394584. doi: 10.1080/07853890.2024.2394584. Epub 2024 Aug 25. PMID: 39183455; PMCID: PMC11348813.
7: Shilnikova K, Kang KA, Piao MJ, Herath HMUL, Fernando PDSM, Boo HJ, Yoon SP, Hyun JW. Shikonin protects skin cells against oxidative stress and cellular dysfunction induced by fine particulate matter. Cell Biol Int. 2024 Aug 21. doi: 10.1002/cbin.12233. Epub ahead of print. PMID: 39169545.
8: Lian B, Zhang J, Yin X, Wang J, Li L, Ju Q, Wang Y, Jiang Y, Liu X, Chen Y, Tang X, Sun C. SIRT1 improves lactate homeostasis in the brain to alleviate parkinsonism via deacetylation and inhibition of PKM2. Cell Rep Med. 2024 Aug 20;5(8):101684. doi: 10.1016/j.xcrm.2024.101684. Epub 2024 Aug 10. PMID: 39128469; PMCID: PMC11384727.
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13: Guo C, Li Y, Zhang H, Zhang Q, Wu X, Wang Y, Sun F, Shi S, Xia X. A review on improving the sensitivity and color stability of naturally sourced pH- sensitive indicator films. Compr Rev Food Sci Food Saf. 2024 Jul;23(4):e13390. doi: 10.1111/1541-4337.13390. PMID: 39031881.
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15: Shi C, Qi Z, Yang C, Luo S, Huang S, Luo Y. Shikonin ameliorates depressive- and anxiogenic-like behaviors in rats via the suppression of inflammation in the hippocampus. Neurosci Lett. 2024 Aug 10;837:137893. doi: 10.1016/j.neulet.2024.137893. Epub 2024 Jul 10. PMID: 38997082.
16: Diane A, Ben Tahar S, El Mrabet A, Rabie R, Saffaj T, Ihssane B. QSAR modeling for cytotoxicity of sulfur-containing Shikonin oxime derivatives targeting HCT-15, MGC-803, BEL-7402, and MCF-7 cell lines. Toxicol In Vitro. 2024 Oct;100:105892. doi: 10.1016/j.tiv.2024.105892. Epub 2024 Jul 10. PMID: 38996828.
17: Lu Y, Zhou H, Han C, Gong Y, Li Y, Xia Y, Liang B, Yang H, Wang Z. Enhanced therapeutic impact of Shikonin-encapsulated exosomes in the inhibition of colorectal cancer progression. Nanotechnology. 2024 Jul 23;35(41). doi: 10.1088/1361-6528/ad61f2. PMID: 38991510.
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