MedKoo Cat#: 573233 | Name: Moxisylyte hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Moxisylyte hydrochloride is an alpha-adrenergic blocking agent that is used in Raynaud's disease. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents.

Chemical Structure

Moxisylyte hydrochloride
Moxisylyte hydrochloride
CAS#964-52-3

Theoretical Analysis

MedKoo Cat#: 573233

Name: Moxisylyte hydrochloride

CAS#: 964-52-3

Chemical Formula: C16H26ClNO3

Exact Mass: 315.1601

Molecular Weight: 315.84

Elemental Analysis: C, 60.85; H, 8.30; Cl, 11.22; N, 4.43; O, 15.20

Price and Availability

Size Price Availability Quantity
1g USD 240.00
5g USD 700.00
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Related CAS #
No Data
Synonym
Arlitene, Carlytene, Enfrental, Limatene, M-101, Moxilite, Enfrental Limatene M-101 Moxilite Moxisylyte HCl, Moxisylyte hydrochloride, Opilon
IUPAC/Chemical Name
Carvacrol, 5-(2-(dimethylamino)ethoxy)-, acetate (ester), hydrochloride (8CI)
InChi Key
IPWGSXZCDPTDEH-UHFFFAOYSA-N
InChi Code
1S/C16H25NO3.ClH/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6;/h9-11H,7-8H2,1-6H3;1H
SMILES Code
c1(c(cc(C)c(c1)OC(C)=O)OCC[NH+](C)C)C(C)C.[ClH-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Moxisylyte (hydrochloride) is (alpha 1-blocker) antagonist.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMSO 41.5 131.40
Water 50.0 158.31
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 315.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Marquer C, Bressolle F. Moxisylyte: a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence. Fundam Clin Pharmacol. 1998;12(4):377-87. Review. PubMed PMID: 9711459. 2: Costa P, Sarrazin B, Bressolle F, Colson MH, Bondil P, Saudubray F. Efficiency and side effects of intracavernous injections of moxisylyte in impotent patients: a dose-finding study versus placebo. J Urol. 1993 Feb;149(2):301-5. PubMed PMID: 8426406. 3: Costa P, Bressolle F, Bromet-Petit M, Mosser J, Sarrazin B. Pharmacokinetics of moxisylyte in healthy volunteers after intravenous and oral administration. J Pharm Sci. 1992 Dec;81(12):1223-6. PubMed PMID: 1491345. 4: Doughty MJ, Lyle WM. A review of the clinical pharmacokinetics of pilocarpine, moxisylyte (thymoxamine), and dapiprazole in the reversal of diagnostic pupillary dilation. Optom Vis Sci. 1992 May;69(5):358-68. Review. PubMed PMID: 1350669.