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MedKoo Cat#: 530801 | Name: Lysyl ornithine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lysyl ornithine is a bioactive chemical.

Chemical Structure

Lysyl ornithine
Lysyl ornithine
CAS#788121-81-3

Theoretical Analysis

MedKoo Cat#: 530801

Name: Lysyl ornithine

CAS#: 788121-81-3

Chemical Formula: C11H24N4O3

Exact Mass: 260.1848

Molecular Weight: 260.34

Elemental Analysis: C, 50.75; H, 9.29; N, 21.52; O, 18.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Lysyl ornithine
IUPAC/Chemical Name
L-Ornithine, N2-L-lysyl-
InChi Key
FNTNTMPEEZFWOQ-IUCAKERBSA-N
InChi Code
InChI=1S/C11H24N4O3/c12-6-2-1-4-8(14)10(16)15-9(11(17)18)5-3-7-13/h8-9H,1-7,12-14H2,(H,15,16)(H,17,18)/t8-,9-/m0/s1
SMILES Code
NCCC[C@@H](C(O)=O)NC([C@H](CCCCN)N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 260.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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A role for both conformational selection and induced fit in ligand binding by the LAO protein. PLoS Comput Biol. 2011 May;7(5):e1002054. doi: 10.1371/journal.pcbi.1002054. Epub 2011 May 26. PubMed PMID: 21637799; PubMed Central PMCID: PMC3102756. 11: Silva DA, Domínguez-Ramírez L, Rojo-Domínguez A, Sosa-Peinado A. Conformational dynamics of L-lysine, L-arginine, L-ornithine binding protein reveals ligand-dependent plasticity. Proteins. 2011 Jul;79(7):2097-108. doi: 10.1002/prot.23030. Epub 2011 May 2. PubMed PMID: 21538545. 12: Ghysels A, Van Speybroeck V, Pauwels E, Catak S, Brooks BR, Van Neck D, Waroquier M. Comparative study of various normal mode analysis techniques based on partial Hessians. J Comput Chem. 2010 Apr 15;31(5):994-1007. doi: 10.1002/jcc.21386. PubMed PMID: 19813181; PubMed Central PMCID: PMC4245204. 13: Burns MR, Graminski GF, Weeks RS, Chen Y, O'Brien TG. Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor. J Med Chem. 2009 Apr 9;52(7):1983-93. doi: 10.1021/jm801580w. PubMed PMID: 19281226; PubMed Central PMCID: PMC2714422. 14: Yang AY, Mancera RL. Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein. J Comput Aided Mol Des. 2008 Nov;22(11):799-814. doi: 10.1007/s10822-008-9215-6. Epub 2008 Apr 15. PubMed PMID: 18415021. 15: Hall BA, Kaye SL, Pang A, Perera R, Biggin PC. Characterization of protein conformational states by normal-mode frequencies. J Am Chem Soc. 2007 Sep 19;129(37):11394-401. Epub 2007 Aug 23. PubMed PMID: 17715919. 16: Pavar MC, Hanif K, Azam A, Lata S, Qadar Pasha MA, Pasha S. 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