Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg | CAS#118675-77-7

MedKoo Cat#: 530799 | Name: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg is a protein kinase C substrate.

Chemical Structure

Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

CAS#118675-77-7

Theoretical Analysis

MedKoo Cat#: 530799

Name: Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

CAS#: 118675-77-7

Chemical Formula: C56H110N22O14

Exact Mass: 1314.8572

Molecular Weight: 1315.64

Elemental Analysis: C, 51.12; H, 8.43; N, 23.42; O, 17.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Lys-arg-ala-lys-ala-lys-thr-thr-lys-lys-arg

IUPAC/Chemical Name

L-Arginine, N2-(N2-(N2-(N-(N-(N2-(N-(N2-(N-(N2-L-lysyl-L-arginyl)-L-alanyl)-L-lysyl)-L-alanyl)-L-lysyl)-L-threonyl)-L-threonyl)-L-lysyl)-L-lysyl)-

InChi Key

VBMOHECZZWVLFJ-GXTUVTBFSA-N

InChi Code

InChI=1S/C56H110N22O14/c1-31(70-48(85)40(22-15-29-67-55(63)64)73-46(83)35(62)17-5-10-24-57)44(81)71-36(18-6-11-25-58)47(84)69-32(2)45(82)72-39(21-9-14-28-61)51(88)77-43(34(4)80)53(90)78-42(33(3)79)52(89)75-38(20-8-13-27-60)49(86)74-37(19-7-12-26-59)50(87)76-41(54(91)92)23-16-30-68-56(65)66/h31-43,79-80H,5-30,57-62H2,1-4H3,(H,69,84)(H,70,85)(H,71,81)(H,72,82)(H,73,83)(H,74,86)(H,75,89)(H,76,87)(H,77,88)(H,78,90)(H,91,92)(H4,63,64,67)(H4,65,66,68)/t31-,32-,33+,34+,35-,36-,37-,38-,39-,40-,41-,42-,43-/m0/s1

SMILES Code

N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H]([C@H](O)C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,315.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tu WZ, Li B, Huang B, Wang Y, Liu XD, Guan H, Zhang SM, Tang Y, Rang WQ, Zhou PK. γH2AX foci formation in the absence of DNA damage: mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway. FEBS Lett. 2013 Nov 1;587(21):3437-43. doi: 10.1016/j.febslet.2013.08.028. Epub 2013 Sep 8. PubMed PMID: 24021642. 2: Sakata K, Matsumoto Y, Tauchi H, Satoh M, Oouchi A, Nagakura H, Koito K, Hosoi Y, Suzuki N, Komatsu K, Hareyama M. Expression of genes involved in repair of DNA double-strand breaks in normal and tumor tissues. Int J Radiat Oncol Biol Phys. 2001 Jan 1;49(1):161-7. PubMed PMID: 11163510. 3: Grode SH, Strother DS, Runge TA, Dobrowolski PJ. Hydrogen fluoride catalyzed migration of side chain protecting groups onto Fmoc during solid phase peptide synthesis. Characterization by CF-FAB analysis of carboxypeptidase digestions and NMR spectroscopy. Int J Pept Protein Res. 1992 Dec;40(6):538-45. PubMed PMID: 1286938.