MedKoo Cat#: 573232 | Name: Moxisylyte

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. Moxisylyte is also used for the short-term treatment of primary Reynaud's syndrome, a condition where the fingers and toes become discoloured in response to cold or emotional distress. Moxisylyte helps by improving blood circulation to the extremities. It is also used locally in the eye to reverse the mydriasis caused by phenylephrine and other sympathomimetic agents.

Chemical Structure

Moxisylyte
Moxisylyte
CAS#54-32-0

Theoretical Analysis

MedKoo Cat#: 573232

Name: Moxisylyte

CAS#: 54-32-0

Chemical Formula: C16H25NO3

Exact Mass: 279.1834

Molecular Weight: 279.38

Elemental Analysis: C, 68.79; H, 9.02; N, 5.01; O, 17.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Arlytene, Moxisylyte, Opilon, Thymoxamine
IUPAC/Chemical Name
(2-(4-Acetoxy-2-isopropyl-5-methylphenoxy)ethyl)dimethylamine
InChi Key
VRYMTAVOXVTQEF-UHFFFAOYSA-N
InChi Code
1S/C16H25NO3/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6/h9-11H,7-8H2,1-6H3
SMILES Code
c1(c(cc(C)c(c1)OC(C)=O)OCCN(C)C)C(C)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 279.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Marquer C, Bressolle F. Moxisylyte: a review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence. Fundam Clin Pharmacol. 1998;12(4):377-87. Review. PubMed PMID: 9711459. 2: Costa P, Sarrazin B, Bressolle F, Colson MH, Bondil P, Saudubray F. Efficiency and side effects of intracavernous injections of moxisylyte in impotent patients: a dose-finding study versus placebo. J Urol. 1993 Feb;149(2):301-5. PubMed PMID: 8426406. 3: Costa P, Bressolle F, Bromet-Petit M, Mosser J, Sarrazin B. Pharmacokinetics of moxisylyte in healthy volunteers after intravenous and oral administration. J Pharm Sci. 1992 Dec;81(12):1223-6. PubMed PMID: 1491345. 4: Doughty MJ, Lyle WM. A review of the clinical pharmacokinetics of pilocarpine, moxisylyte (thymoxamine), and dapiprazole in the reversal of diagnostic pupillary dilation. Optom Vis Sci. 1992 May;69(5):358-68. Review. PubMed PMID: 1350669.