MedKoo Cat#: 573227 | Name: Ardisin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ardisin is a Topoisomerase I and II enzyme inhibitor. Ardisin may have antioxidant effects.

Chemical Structure

Ardisin
CAS#72629-62-0

Theoretical Analysis

MedKoo Cat#: 573227

Name: Ardisin

CAS#: 72629-62-0

Chemical Formula: C20H32O2

Exact Mass: 304.2402

Molecular Weight: 304.47

Elemental Analysis: C, 78.90; H, 10.59; O, 10.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Ardisin
IUPAC/Chemical Name
1,3-Benzenediol, 2-methyl-5-(8-tridecenyl)-, (Z)-
InChi Key
AAFWHAONVYRTMW-SREVYHEPSA-N
InChi Code
1S/C20H32O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-18-15-19(21)17(2)20(22)16-18/h6-7,15-16,21-22H,3-5,8-14H2,1-2H3/b7-6-
SMILES Code
c1(c(c(cc(c1)CCCCCCC\C=C/CCCC)O)C)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 304.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: de Mejía EG, Chandra S, Ramírez-Mares M, Wang W. Catalytic inhibition of human DNA topoisomerase by phenolic compounds in Ardisia compressa extracts and their effect on human colon cancer cells. Food Chem Toxicol. 2006 Aug;44(8):1191-203. Epub 2006 Mar 15. PubMed PMID: 16540225. 2: Ramírez-Mares MV, de Mejía EG. Comparative study of the antioxidant effect of ardisin and epigallocatechin gallate in rat hepatocytes exposed to benomyl and 1-nitropyrene. Food Chem Toxicol. 2003 Nov;41(11):1527-35. PubMed PMID: 12963005. 3: González de Mejía E, Ramírez-Mares MV, Nair MG. Topoisomerase I and II enzyme inhibitory aqueous extract of Ardisia compressa and ardisin protect against benomyl oxidation of hepatocytes. J Agric Food Chem. 2002 Dec 18;50(26):7714-9. PubMed PMID: 12475294.