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MedKoo Cat#: 564677 | Name: DMNP-EDTA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DMNP-EDTA is a caged Ca2+ chelator which photouncages Cu2+ ions for light-controlled gene expression in yeast.

Chemical Structure

DMNP-EDTA
DMNP-EDTA
CAS#117367-86-9

Theoretical Analysis

MedKoo Cat#: 564677

Name: DMNP-EDTA

CAS#: 117367-86-9

Chemical Formula: C18H23N3O12

Exact Mass: 473.1282

Molecular Weight: 473.39

Elemental Analysis: C, 45.67; H, 4.90; N, 8.88; O, 40.56

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
DMNPEDTA; DMNP EDTA; DMNP-EDTA; DM-Nitrophen; DM Nitrophen
IUPAC/Chemical Name
1-(2-Nitro-4,5-dimethoxyphenyl)-N,N,N',N'-tetrakis[(oxycarbonyl)methyl]-1,2-ethanediamine
InChi Key
FKXGYESXGMKAKC-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H23N3O12/c1-32-13-3-10(11(21(30)31)4-14(13)33-2)12(20(8-17(26)27)9-18(28)29)5-19(6-15(22)23)7-16(24)25/h3-4,12H,5-9H2,1-2H3,(H,22,23)(H,24,25)(H,26,27)(H,28,29)
SMILES Code
O=C(CN(CC(O)=O)CC(C1=CC(OC)=C(OC)C=C1[N+]([O-])=O)N(CC(O)=O)CC(O)=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 473.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kusen PM, Wandrey G, Krewald V, Holz M, Berstenhorst SMZ, Büchs J, Pietruszka J. Light-controlled gene expression in yeast using photocaged Cu(2). J Biotechnol. 2017 Sep 20;258:117-125. doi: 10.1016/j.jbiotec.2017.04.032. Epub 2017 Apr 25. PubMed PMID: 28455204. 2: Wang M, Chen Z, Xing Y, Zhang X, Dong XZ, Ji GJ. Localized Ca2+ uncaging induces Ca2+ release through IP3R in smooth muscle. Acta Pharmacol Sin. 2006 Jul;27(7):939-44. PubMed PMID: 16787580. 3: Ji G, Feldman M, Doran R, Zipfel W, Kotlikoff MI. Ca2+ -induced Ca2+ release through localized Ca2+ uncaging in smooth muscle. J Gen Physiol. 2006 Mar;127(3):225-35. PubMed PMID: 16505145; PubMed Central PMCID: PMC2151500. 4: Ullrich ND, Voets T, Prenen J, Vennekens R, Talavera K, Droogmans G, Nilius B. Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice. Cell Calcium. 2005 Mar;37(3):267-78. PubMed PMID: 15670874.