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MedKoo Cat#: 573207 | Name: Aptocaine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aptocaine is a local anesthetic. It is related toprilocaine; like prilocaine, it has a low sub-cutaneous toxicity, but preliminary studies suggest that, unlike prilocaine, it does not induce methaemoglobinaemia.

Chemical Structure

Aptocaine
CAS#19281-29-9

Theoretical Analysis

MedKoo Cat#: 573207

Name: Aptocaine

CAS#: 19281-29-9

Chemical Formula: C14H20N2O

Exact Mass: 232.1576

Molecular Weight: 232.33

Elemental Analysis: C, 72.38; H, 8.68; N, 12.06; O, 6.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Aptocaine
IUPAC/Chemical Name
N-(2-(1-Pyrrolidinyl)propionyl)-o-toluidine
InChi Key
WJOQWLQQCYYQBE-UHFFFAOYSA-N
InChi Code
1S/C14H20N2O/c1-11-7-3-4-8-13(11)15-14(17)12(2)16-9-5-6-10-16/h3-4,7-8,12H,5-6,9-10H2,1-2H3,(H,15,17)
SMILES Code
Cc1ccccc1NC(=O)C(C)N2CCCC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 232.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Beckett AH, Vuthikongsirigool W. Identification of metabolites of aptocaine and some related compounds [proceedings]. J Pharm Pharmacol. 1976 Dec;28 Suppl:54P. PubMed PMID: 12331. 2: Reynolds F, Bryson TH, Nicholas AD. Intradermal study of a new local anaesthetic agent aptocaine. Br J Anaesth. 1976 Apr;48(4):347-54. PubMed PMID: 776194. 3: Blanchard J, Lasserre P, Panak E, Ricoeur M. [Comparative double-blind tests of aptocaine. Methodology and analysis of results]. Chir Dent Fr. 1975 Sep 3;45(268):53-7. French. PubMed PMID: 801457.