MedKoo Cat#: 573201 | Name: APP-CHMINACA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

APP-CHMINACA is a synthetic cannabinoid (CB) featuring a 1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (CHMINACA) base. It displays a 10-fold greater affinity for the central CB1 receptor than that of JWH 018.

Chemical Structure

APP-CHMINACA
APP-CHMINACA
CAS#1185887-14-2

Theoretical Analysis

MedKoo Cat#: 573201

Name: APP-CHMINACA

CAS#: 1185887-14-2

Chemical Formula: C24H28N4O2

Exact Mass: 404.2212

Molecular Weight: 404.51

Elemental Analysis: C, 71.26; H, 6.98; N, 13.85; O, 7.91

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
No Data
Synonym
APP-CHMINACA, APP-CHMINACA RME, PX-3-, PX-3, PX3
IUPAC/Chemical Name
1H-Indazole-3-carboxamide, N-((1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl)-1-(cyclohexylmethyl)-
InChi Key
DMHWDSGURMXMGE-FQEVSTJZSA-N
InChi Code
1S/C24H28N4O2/c25-23(29)20(15-17-9-3-1-4-10-17)26-24(30)22-19-13-7-8-14-21(19)28(27-22)16-18-11-5-2-6-12-18/h1,3-4,7-10,13-14,18,20H,2,5-6,11-12,15-16H2,(H2,25,29)(H,26,30)/t20-/m0/s1
SMILES Code
NC(=O)[C@H](Cc1ccccc1)NC(=O)c2nn(CC3CCCCC3)c4ccccc24
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 404.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Doi T, Tagami T, Takeda A, Asada A, Sawabe Y. Evaluation of carboxamide-type synthetic cannabinoids as CB(1)/CB(2) receptor agonists: difference between the enantiomers. Forensic Toxicol. 2018;36(1):51-60. doi: 10.1007/s11419-017-0378-5. Epub 2017 Aug 4. PubMed PMID: 29367862; PubMed Central PMCID: PMC5754384.