SRI-37683 is a GLUT inhibitor which preferentially inhibits the growth of GBM cells with minimal toxicity to non-neoplastic astrocytes and neurons. SRI-37683 also inhibits glucose uptake and decreases the glycolytic capacity and glycolytic reserve capacity of GBM patient-derived xenograft (PDX) cells in glycolytic stress test assays.
MedKoo Cat#: 564661
Name: SRI-37683
CAS#: NONE
Chemical Formula: C19H17N5O2S
Exact Mass: 379.1103
Molecular Weight: 379.44
Elemental Analysis: C, 60.14; H, 4.52; N, 18.46; O, 8.43; S, 8.45
The following data is based on the product molecular weight 379.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
