SRI-37684 is a GLUT inhibitor which preferentially inhibits the growth of GBM cells with minimal toxicity to non-neoplastic astrocytes and neurons. SRI-37684 also inhibits glucose uptake and decreases the glycolytic capacity and glycolytic reserve capacity of GBM patient-derived xenograft (PDX) cells in glycolytic stress test assays.
MedKoo Cat#: 564660
Name: SRI-37684
CAS#: NONE
Chemical Formula: C23H18N4O2
Exact Mass: 382.1430
Molecular Weight: 382.42
Elemental Analysis: C, 72.24; H, 4.74; N, 14.65; O, 8.37
The following data is based on the product molecular weight 382.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |