MedKoo Cat#: 584727 | Name: TM N1324
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TM N1324 is a potent and selective GPR39 agonist and is orally bioavailable.

Chemical Structure

TM N1324
CAS#1144477-35-9

Theoretical Analysis

MedKoo Cat#: 584727

Name: TM N1324

CAS#: 1144477-35-9

Chemical Formula: C18H13ClFN7O

Exact Mass: 397.0854

Molecular Weight: 397.80

Elemental Analysis: C, 54.35; H, 3.29; Cl, 8.91; F, 4.78; N, 24.65; O, 4.02

Price and Availability

Size Price Availability Quantity
5mg USD 310.00
25mg USD 800.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
TM N1324
IUPAC/Chemical Name
4-(2-Chloro-4-fluorophenyl)-1,4,5,7-tetrahydro-3-methyl-1-(9H-purin-6-yl)-6H-pyrazolo[3,4-b]pyridin-6-one
InChi Key
CYQNVXRIWKKWQG-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H13ClFN7O/c1-8-14-11(10-3-2-9(20)4-12(10)19)5-13(28)25-17(14)27(26-8)18-15-16(22-6-21-15)23-7-24-18/h2-4,6-7,11H,5H2,1H3,(H,25,28)(H,21,22,23,24)
SMILES Code
O=C1CC(C2=CC=C(F)C=C2Cl)C3=C(N(C4=C5N=CNC5=NC=N4)N=C3C)N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 397.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Frimurer et al (2017) Model-based discovery of synthetic agonists for the Zn2+-sensing G-protein-coupled receptor 39 (GPR39) reveals novel biological functions. J.Med.Chem. 60 886 PMID: 28045522