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MedKoo Cat#: 581648 | Name: Dextranomer
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dextranomer, for treatment of burns; consists of three-dimensional network of dextran polymers cross-linked by epichlorohydrin; dextranomer based implants usedas a bulking agent for endoscopic treatment of pediatric structural incontinence; ingredient of dextranomer-hyaluronic acid copolymer which is used to treat primary vesicoureteral reflux.

Chemical Structure

Dextranomer
Dextranomer
CAS#56087-11-7

Theoretical Analysis

MedKoo Cat#: 581648

Name: Dextranomer

CAS#: 56087-11-7

Chemical Formula:

Exact Mass: 0.0000

Molecular Weight: 0.00

Elemental Analysis:

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 Back order
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Related CAS #
No Data
Synonym
Dextranomer; Debrisan; Dextranomere; Dextranomero; Dextranomerum.
IUPAC/Chemical Name
None
InChi Key
None
InChi Code
None
SMILES Code
O1[C@@H]([C@@H](O)[C@@H]([C@H](O)[C@H]1O*)O)CO[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)OCC(CO[C@@H]1[C@H](O[C@@H]([C@@H]([C@H]1O)O)OC[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O*)O)O)O)CO[C@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)C*)O)CO[C@H]1O[C@H](C*)[C@@H](O)[C@@H](O)[C@H]1O
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang PZT, Abdelhalim A, Walia A, Wehbi E, Dave S, Khoury A. Avoiding routine postoperative voiding cystourethrogram: Predicting radiologic success for endoscopically treated vesicoureteral reflux. Can Urol Assoc J. 2018 Nov 5. doi: 10.5489/cuaj.5589. [Epub ahead of print] PubMed PMID: 30407152. 2: Lüttmann K, Merle R, Nickel R. Retrospective analysis after endoscopic urethral injections of glutaraldehyde-cross-linked-collagen or dextranomer/hyaluronic acid copolymer in bitches with urinary incontinence. J Small Anim Pract. 2018 Nov 2. doi: 10.1111/jsap.12949. [Epub ahead of print] PubMed PMID: 30387491. 3: Han DS, Cambareri G, Alagiri M, Chiang G. Reflux Timing Is a Predictor of Successful Endoscopic Treatment of Vesicoureteral Reflux. Urology. 2018 Oct 29. pii: S0090-4295(18)31088-4. doi: 10.1016/j.urology.2018.09.034. [Epub ahead of print] PubMed PMID: 30385258. 4: Dalkiliç A, Bayar G, Demirkan H, Horasanli K. The learning curve of sting method for endoscopic injection treatment of vesicoureteral reflux. Int Braz J Urol. 2018 Nov-Dec;44(6):1200-1206. doi: 10.1590/S1677-5538.IBJU.2017.0465. PubMed PMID: 30325598. 5: Wu HY, Concepcion W, Grimm PC. When does vesicoureteral reflux in pediatric kidney transplant patients need treatment? Pediatr Transplant. 2018 Dec;22(8):e13299. doi: 10.1111/petr.13299. Epub 2018 Oct 15. PubMed PMID: 30324753. 6: Bele U, Bratus D. Dextranomer-Hyaluronic Acid and Polyacrylate-Polyalcohol Copolymer are Equally Efficient for Endoscopic Treatment of Vesicoureteral Reflux in Children. Urol J. 2018 Oct 8. doi: 10.22037/uj.v0i0.4462. [Epub ahead of print] PubMed PMID: 30318569. 7: Peck BW, Baas BS, Cofer SA. Injection Pharyngoplasty With a Hyaluronic Acid and Dextranomer Copolymer to Treat Velopharyngeal Insufficiency in Adults. Mayo Clin Proc Innov Qual Outcomes. 2017 Aug 2;1(2):176-184. doi: 10.1016/j.mayocpiqo.2017.06.003. eCollection 2017 Sep. PubMed PMID: 30225414; PubMed Central PMCID: PMC6134910. 8: Choi W, Nam W, Lee C, Han JH, Shin JH, Kim KS, Song SH. Long-term Outcomes of Endoscopic Anti-reflux Surgery in Pediatric Patients with Vesicoureteral Reflux: Urinary Tract Infection, Renal Scarring, and Predictive Factors for Success. J Korean Med Sci. 2018 Aug 8;33(38):e240. doi: 10.3346/jkms.2018.33.e240. eCollection 2018 Sep 17. PubMed PMID: 30224908; PubMed Central PMCID: PMC6137031. 9: Alizadeh F, Omidi I, Haghdani S, Hatef Khorrami M, Izadpanahi MH, Mohammadi Sichani M. A comparison between dextranomer/ hyaluronic acid and polyacrylate polyalcohol copolymer as bulking agents for treating primary vesicoureteral reflux. Urol J. 2018 Aug 26. doi: 10.22037/uj.v0i0.4156. [Epub ahead of print] PubMed PMID: 30178456. 10: Izol V, Kuyucu Y, Acikalin A, Deger M, Aridogan IA, Polat S, Satar N. Evaluation of the intravesical ureters after failed endoscopic treatment of vesicoureteral reflux with dextranomer/hyaluronic acid in children via light and transmission electron microscopic analysis. A Matched Case-Control Study. Urol J. 2018 Aug 26. doi: 10.22037/uj.v0i0.4281. [Epub ahead of print] PubMed PMID: 30178448. 11: Arena S, Romeo C. Comment on "Subureteral Injection with Small-Size Dextranomer/Hyaluronic Acid Copolymer: Is It Really Efficient?" Biomed Res Int. 2018 Aug 12;2018:4078183. doi: 10.1155/2018/4078183. eCollection 2018. PubMed PMID: 30159327; PubMed Central PMCID: PMC6109544. 12: Faure A, Haddad M, Hery G, Merrot T, Guys JM. Endoscopic injection of bulking agent around the ejaculatory ducts at the verumontanum for recurrent paediatric epididymitis. J Pediatr Urol. 2018 Oct;14(5):476-482. doi: 10.1016/j.jpurol.2018.06.014. Epub 2018 Aug 25. PubMed PMID: 30154047. 13: Irwin T, Snow AR, Orton TS, Elliott C. Endoscopic, Ultrasonographic, and Histologic Descriptions of Dextranomer/Hyaluronic Acid in a Case of Fecal Incontinence. Case Rep Pathol. 2018 Jul 26;2018:5873094. doi: 10.1155/2018/5873094. eCollection 2018. PubMed PMID: 30147980; PubMed Central PMCID: PMC6083641. 14: Harper L, Paillet P, Minvielle T, Dobremez E, Lefevre Y, Bouali O, Abbo O. Long-Term (>10 Years) Results After Endoscopic Injection Therapy for Vesicoureteral Reflux. J Laparoendosc Adv Surg Tech A. 2018 Nov;28(11):1408-1411. doi: 10.1089/lap.2018.0035. Epub 2018 Jul 23. PubMed PMID: 30036128. 15: Tiernan J, Bhatt A, Liska D. An Unusual Case of Submucosal Rectal Nodules. Gastroenterology. 2018 Oct;155(4):e5-e6. doi: 10.1053/j.gastro.2018.05.044. Epub 2018 Jun 6. PubMed PMID: 29885317. 16: Olson JK, Navarro JB, Allen JM, McCulloh CJ, Mashburn-Warren L, Wang Y, Varaljay VA, Bailey MT, Goodman SD, Besner GE. An enhanced Lactobacillus reuteri biofilm formulation that increases protection against experimental necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol. 2018 Sep 1;315(3):G408-G419. doi: 10.1152/ajpgi.00078.2018. Epub 2018 May 31. PubMed PMID: 29848024. 17: Kim SW, Lee YS, Im YJ, Han SW. New bulking agent for the treatment of vesicoureteral reflux: Polymethylmethacrylate/dextranomer. Investig Clin Urol. 2018 May;59(3):206-212. doi: 10.4111/icu.2018.59.3.206. Epub 2018 Apr 10. PubMed PMID: 29744479; PubMed Central PMCID: PMC5934284. 18: García-Aparicio L, Blázquez-Gómez E, Martin O, Pérez-Bertólez S, Arboleda J, Soria A, Tarrado X. Randomized clinical trial between polyacrylate-polyalcohol copolymer (PPC) and dextranomer-hyaluronic acid copolymer (Dx/HA) as bulking agents for endoscopic treatment of primary vesicoureteral reflux (VUR). World J Urol. 2018 Oct;36(10):1651-1656. doi: 10.1007/s00345-018-2314-7. Epub 2018 May 3. PubMed PMID: 29725806. 19: Bozkurt M, Agalarov S, Merder E, Altunrende F. Dextranomer/Hyaluronic Acid Calcification Masquerading as Distal Ureteral Calculi in a Patient Previously Treated for Vesicoureteral Reflux. J Endourol Case Rep. 2018 Apr 1;4(1):51-52. doi: 10.1089/cren.2017.0051. eCollection 2018. PubMed PMID: 29675477; PubMed Central PMCID: PMC5905864. 20: Gomez Lujan M, Velarde L, Cruzalegui C, Berrios C, Sifuentes E, Gálvez J, Soto H, Castañeda E, Bazán G, Nakachi A, Chambi M, Medina C, Torres A. Endoscopic Treatment for Vesicoureteral Reflux in Recurrent Urinary Tract Infections in Kidney Transplant: Experience of One Center. Transplant Proc. 2018 Mar;50(2):513-515. doi: 10.1016/j.transproceed.2018.01.007. PubMed PMID: 29579838.