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MedKoo Cat#: 573189 | Name: AP-811
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

AP-811 is a derivative of the Phe(8)-Ile(15) region of atrial natriuretic peptide (ANP) which acts as a ANP-C receptor selective agonist.

Chemical Structure

AP-811
AP-811
CAS#124833-45-0

Theoretical Analysis

MedKoo Cat#: 573189

Name: AP-811

CAS#: 124833-45-0

Chemical Formula: C46H66N12O8

Exact Mass: 914.5127

Molecular Weight: 915.11

Elemental Analysis: C, 60.38; H, 7.27; N, 18.37; O, 13.99

Price and Availability

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1mg USD 485.00 2 Weeks
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Related CAS #
No Data
Synonym
AP 811; AP-811; AP811
IUPAC/Chemical Name
(S)-3-((2S,3S)-2-((S)-2-(2-(4-(2-naphthamido)phenyl)acetamido)-5-guanidinopentanamido)-3-methylpentanamido)-4-((S)-5-guanidino-2-(((S)-2-methylbutyl)amino)pentanamido)-4-oxobutanoic acid
InChi Key
CWKUICQDCFQXIS-OCFLPWLCSA-N
InChi Code
InChI=1S/C46H66N12O8/c1-5-27(3)26-53-34(13-9-21-51-45(47)48)41(63)58-43(65)36(25-38(60)61)56-44(66)39(28(4)6-2)57-42(64)35(14-10-22-52-46(49)50)55-37(59)23-29-15-19-33(20-16-29)54-40(62)32-18-17-30-11-7-8-12-31(30)24-32/h7-8,11-12,15-20,24,27-28,34-36,39,53H,5-6,9-10,13-14,21-23,25-26H2,1-4H3,(H,54,62)(H,55,59)(H,56,66)(H,57,64)(H,60,61)(H4,47,48,51)(H4,49,50,52)(H,58,63,65)/t27-,28-,34-,35-,36-,39-/m0/s1
SMILES Code
C([C@@H](NC[C@H](CC)C)CCCNC(=N)N)(=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)Cc1ccc(cc1)NC(=O)c1cc2ccccc2cc1)CCCNC(=N)N)=O)[C@H](CC)C)=O)CC(=O)O)=O
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 915.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wegner M, Stasch JP, Hirth-Dietrich C, Dressel J, Voges KP, Kazda S. Interaction of a neutral endopeptidase inhibitor with an ANP-C receptor ligand in anesthetized dogs. Clin Exp Hypertens. 1995 Aug;17(6):861-76. PubMed PMID: 7581258. 2: Koyama S, Inoue T, Terai T, Takimoto K, Kato M, Ito K, Neya M, Seki J, Kobayashi Y, Kyogoku Y, et al. AP-811, a novel ANP-C receptor selective agonist. Int J Pept Protein Res. 1994 Apr;43(4):332-6. PubMed PMID: 8045678.