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MedKoo Cat#: 584715 | Name: MF 961

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MF 961 is a quinolone antimicrobial with in-vitro activity.

Chemical Structure

MF 961
MF 961
CAS#138372-62-0

Theoretical Analysis

MedKoo Cat#: 584715

Name: MF 961

CAS#: 138372-62-0

Chemical Formula: C18H19F2N3O3S

Exact Mass: 395.1115

Molecular Weight: 395.42

Elemental Analysis: C, 54.67; H, 4.84; F, 9.61; N, 10.63; O, 12.14; S, 8.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MF 961; MF-961
IUPAC/Chemical Name
7H-Pyrido(1,2,3-de)-1,4-benzothiazine-6-carboxylic acid, 9-fluoro-3-(fluoromethyl)-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-
InChi Key
YHMYZZSLDKKBQL-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H19F2N3O3S/c1-21-2-4-22(5-3-21)15-13(20)6-11-14-17(15)27-9-10(7-19)23(14)8-12(16(11)24)18(25)26/h6,8,10H,2-5,7,9H2,1H3,(H,25,26)
SMILES Code
O=C(C(C1=O)=CN2C(CF)CSC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 395.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wise R, Andrews JM, Matthews R, Wolstenholme M. The in-vitro activity of two new quinolones: rufloxacin and MF 961. J Antimicrob Chemother. 1992 Jun;29(6):649-60. PubMed PMID: 1324239. 2: Fabbri S, Broggini M, Pagella P, D'Incalci M. The inhibition of supercoiling activity of DNA gyrase from Micrococcus luteus caused by rufloxacin (MF 934) and MF 961. J Antimicrob Chemother. 1991 May;27(5):687-9. PubMed PMID: 1653205. 3: Piddock LJ, Panchal S, Norte V. Comparison of the mechanism of action and resistance of two new fluoroquinolones, rufloxacin and MF961 with those of ofloxacin and fleroxacin in gram-negative and gram-positive bacteria. J Antimicrob Chemother. 1993 Jun;31(6):855-63. PubMed PMID: 8395493. 4: Piddock LJ, Jin YF, Ricci V, Asuquo AE. Quinolone accumulation by Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. J Antimicrob Chemother. 1999 Jan;43(1):61-70. PubMed PMID: 10381102.