JC-171 is an NLRP3 inflammasome inhibitor with biological activity in vivo, for potential treatment of multiple sclerosis. JC-171 treatment was shown to delay the progression and reduce the severity of experimental autoimmune encephalomyelitis (EAE), and a mouse model of MS, in both prophylactic and therapeutic settings.
MedKoo Cat#: 564583
Name: JC-171
CAS#: 2112809-98-8
Chemical Formula: C16H17ClN2O5S
Exact Mass: 384.0547
Molecular Weight: 384.83
Elemental Analysis: C, 49.94; H, 4.45; Cl, 9.21; N, 7.28; O, 20.79; S, 8.33
The following data is based on the product molecular weight 384.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
