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MedKoo Cat#: 564575 | Name: ZMC3

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZMC3 is a potent iron chelator and antiproliferative agent which exhibits zinc metallochaperone activity and enhanced sensitivity in p53-R175H cell lines.

Chemical Structure

ZMC3
ZMC3
CAS#79514-41-3

Theoretical Analysis

MedKoo Cat#: 564575

Name: ZMC3

CAS#: 79514-41-3

Chemical Formula: C17H20N6Se

Exact Mass: 388.0915

Molecular Weight: 387.35

Elemental Analysis: C, 52.71; H, 5.20; N, 21.70; Se, 20.38

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
NSC328784; NSC-328784; NSC 328784; ZMC-3; ZMC 3; ZMC3
IUPAC/Chemical Name
(E)-4-(Pyridin-2-yl)-N'-(1-(pyridin-2-yl)ethylidene)piperazine-1-carboselenohydrazide
InChi Key
WIUIXGQDLTXGSV-XSFVSMFZSA-N
InChi Code
InChI=1S/C17H20N6Se/c1-14(15-6-2-4-8-18-15)20-21-17(24)23-12-10-22(11-13-23)16-7-3-5-9-19-16/h2-9H,10-13H2,1H3,(H,21,24)/b20-14+
SMILES Code
[Se]=C(N1CCN(C2=NC=CC=C2)CC1)N/N=C(C3=NC=CC=C3)\C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 387.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yu X, Blanden A, Tsang AT, Zaman S, Liu Y, Gilleran J, Bencivenga AF, Kimball SD, Loh SN, Carpizo DR. Thiosemicarbazones Functioning as Zinc Metallochaperones to Reactivate Mutant p53. Mol Pharmacol. 2017 Jun;91(6):567-575. doi: 10.1124/mol.116.107409. Epub 2017 Mar 20. PubMed PMID: 28320780; PubMed Central PMCID: PMC5438133.