MedKoo Cat#: 564573 | Name: 4-CPPC
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

4-CPPC is the first reversible and selective small molecule inhibitor of the pro-inflammatory protein macrophage migration inhibitory factor-2 (a.k.a. MIF-2 or D-DT).

Chemical Structure

4-CPPC
4-CPPC
CAS#29553-70-6

Theoretical Analysis

MedKoo Cat#: 564573

Name: 4-CPPC

CAS#: 29553-70-6

Chemical Formula: C14H9NO6

Exact Mass: 287.0430

Molecular Weight: 287.23

Elemental Analysis: C, 58.54; H, 3.16; N, 4.88; O, 33.42

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,350.00 2 Weeks
1g USD 4,650.00 2 Weeks
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Related CAS #
No Data
Synonym
4CPPC; 4 CPPC; 4-CPPC
IUPAC/Chemical Name
4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid
InChi Key
NBVHLJGGHJLTGM-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H9NO6/c16-12(17)8-3-1-2-7(4-8)9-5-11(14(20)21)15-6-10(9)13(18)19/h1-6H,(H,16,17)(H,18,19)(H,20,21)
SMILES Code
O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 287.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pantouris G, Bucala R, Lolis EJ. Structural Plasticity in the C-Terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor. Biochemistry. 2018 Jul 3;57(26):3599-3605. doi: 10.1021/acs.biochem.8b00344. Epub 2018 Jun 12. PubMed PMID: 29847104; PubMed Central PMCID: PMC6123015.