Synonym
3OFeruloylquinic acid; 3 O-Feruloylquinic acid; 3-OFeruloylquinic acid; 3-O-Feruloylquinic acid; 3 O Feruloylquinic acid
IUPAC/Chemical Name
(1S,3S,4S,5S)-1,3,4-Trihydroxy-5-[(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoyl]oxycyclohexane-1-carboxylic acid
InChi Key
RAGZUCNPTLULOL-ZLCRQKIYSA-N
InChi Code
InChI=1S/C17H20O9/c1-25-12-6-9(2-4-10(12)18)3-5-14(20)26-13-8-17(24,16(22)23)7-11(19)15(13)21/h2-6,11,13,15,18-19,21,24H,7-8H2,1H3,(H,22,23)/b5-3+/t11-,13-,15-,17-/m0/s1
SMILES Code
O=C([C@]1(O)C[C@H](O)[C@H](O)[C@@H](OC(/C=C/C2=CC=C(O)C(OC)=C2)=O)C1)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
368.34
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Liu Y, Deng AJ, Ma L, Zhang HJ, Zhang ZH, Wu LQ, Shen ZF, Wang WJ, Qin HL. [Chemical constituents of the roots of Macleaya microcarpa and activation efficacy of benzophenanthridine alkaloids for the transcription of xbp1 gene]. Yao Xue Xue Bao. 2015 Feb;50(2):207-10. Chinese. PubMed PMID: 25975030.
2: Park JB. Isolation and quantification of major chlorogenic acids in three major instant coffee brands and their potential effects on H2O2-induced mitochondrial membrane depolarization and apoptosis in PC-12 cells. Food Funct. 2013 Nov;4(11):1632-8. doi: 10.1039/c3fo60138b. PubMed PMID: 24061869.
3: Yang YJ, Liu X, Wu HR, He XF, Bi YR, Zhu Y, Liu ZL. Radical scavenging activity and cytotoxicity of active quinic acid derivatives from Scorzonera divaricata roots. Food Chem. 2013 Jun 1;138(2-3):2057-63. doi: 10.1016/j.foodchem.2012.10.122. Epub 2012 Nov 21. PubMed PMID: 23411343.
4: Erel SB, Karaalp C, Bedir E, Kaehlig H, Glasl S, Khan S, Krenn L. Secondary metabolites of Centaurea calolepis and evaluation of cnicin for anti-inflammatory, antioxidant, and cytotoxic activities. Pharm Biol. 2011 Aug;49(8):840-9. doi: 10.3109/13880209.2010.551538. Epub 2011 May 25. PubMed PMID: 21612369.
5: Ge F, Ke C, Tang W, Yang X, Tang C, Qin G, Xu R, Li T, Chen X, Zuo J, Ye Y. Isolation of chlorogenic acids and their derivatives from Stemona japonica by preparative HPLC and evaluation of their anti-AIV (H5N1) activity in vitro. Phytochem Anal. 2007 May-Jun;18(3):213-8. PubMed PMID: 17500364.
