Synonym
Deanol acetamidobenzoate; Cervoxan; Deaner; Deanol p-acetamidobenzoate; Diforene; Elevan; Nervoton.
IUPAC/Chemical Name
2-(Dimethylamino)ethanol p-acetylaminobenzoate
InChi Key
FZLZGULUHIGIOT-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H18N2O3/c1-10(16)14-12-6-4-11(5-7-12)13(17)18-9-8-15(2)3/h4-7H,8-9H2,1-3H3,(H,14,16)
SMILES Code
CN(CCOC(C1=CC=C(NC(C)=O)C=C1)=O)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
250.30
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl). 1979 Nov;65(3):219-23. PubMed PMID: 117492.
3: Millington WR, McCall AL, Wurtman RJ. Deanol acetamidobenzoate inhibits the blood-brain barrier transport of choline. Ann Neurol. 1978 Oct;4(4):302-6. PubMed PMID: 727735.
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9: JACOBS J. A CONTROLLED TRIAL OF DEANER AND A PLACEBO IN MENTALLY DEFECTIVE CHILDREN. Br J Clin Pract. 1965 Feb;19:77-86. PubMed PMID: 14260059.
10: BOSTOCK J, SHACKLETON M. The use of DMAE ("Deaner") in behaviour states. Med J Aust. 1962 Sep 1;49(2):337-9. PubMed PMID: 14014225.
11: REBOLLO MA, CASAS M. [Use of "Deaner" (deanol) in children with clinical and/or electroencephalographic epilepsy]. Arch Pediatr Urug. 1961 Sep;32:514-9. Spanish. PubMed PMID: 14490836.
12: MORIARTY JD, MEBANE JC. Clinical experiences with deanol (deaner): a different type of "psychic energizer". J Neuropsychiatr. 1959 Sep-Oct;1:26-7. PubMed PMID: 14424158.
13: BARSA JA, SAUNDERS JC. Deanol (deaner) in the treatment of schizophrenia. Am J Psychiatry. 1959 Sep;116:255-6. PubMed PMID: 13797141.
14: PENNINGTON VM. Clinical results with the use of deanol (deaner) in schizophrenia. Am J Psychiatry. 1959 Aug;116:165-6. PubMed PMID: 14431616.
15: MORIARTY JD, MEBANE JC. Clinical uses of deanol (deaner): a new type of psychotropic drug. Am J Psychiatry. 1959 Apr;115(10):941-2. PubMed PMID: 13637266.
16: MELLER RL. Treatment of mild depression with deanol para-acetamidobenzoate. J Lancet. 1959 Jan;79(1):25-6. PubMed PMID: 13621059.
17: TOLL N. Deaner an adjunct for treatment of schizoid and schzophrenic patients. Am J Psychiatry. 1958 Oct;115(4):366-7. PubMed PMID: 13583235.
18: LEMERE F, LASATER JH. Deanol (deaner) a new cerebral stimulant for the treatment of neurasthenia and mild depression: a preliminary report. Am J Psychiatry. 1958 Jan;114(7):655-6. PubMed PMID: 13487816.
