Synonym
Panaxynol, (+)-Falcarinol, (+) Falcarinol, Falcarinol
IUPAC/Chemical Name
(3S,9Z)-heptadeca-1,9-dien-4,6-diyn-3-ol
InChi Key
UGJAEDFOKNAMQD-DVQDXYAYSA-N
InChi Code
InChI=1S/C17H24O/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17(18)4-2/h4,10-11,17-18H,2-3,5-9,12H2,1H3/b11-10+/t17-/m0/s1
SMILES Code
C=C[C@H](O)C#CC#CC/C=C/CCCCCCC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
244.38
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Stefanson AL, Bakovic M. Falcarinol Is a Potent Inducer of Heme Oxygenase-1 and Was More Effective than Sulforaphane in Attenuating Intestinal Inflammation at Diet-Achievable Doses. Oxid Med Cell Longev. 2018 Oct 21;2018:3153527. doi: 10.1155/2018/3153527. eCollection 2018. PubMed PMID: 30420908; PubMed Central PMCID: PMC6215554.
2: Busta L, Yim W, LaBrant EW, Wang P, Grimes L, Malyszka K, Cushman JC, Santos P, Kosma DK, Cahoon EB. Identification of genes encoding enzymes catalyzing the early steps of carrot polyacetylene biosynthesis. Plant Physiol. 2018 Oct 17. pii: pp.01195.2018. doi: 10.1104/pp.18.01195. [Epub ahead of print] PubMed PMID: 30333150.
3: Kobaek-Larsen M, Nielsen DS, Kot W, Krych Ł, Christensen LP, Baatrup G. Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer. BMC Res Notes. 2018 Jun 27;11(1):411. doi: 10.1186/s13104-018-3527-y. PubMed PMID: 29945666; PubMed Central PMCID: PMC6020439.
4: Medbouhi A, Merad N, Khadir A, Bendahou M, Djabou N, Costa J, Muselli A. Chemical Composition and Biological Investigations of Eryngium triquetrum Essential Oil from Algeria. Chem Biodivers. 2018 Jan;15(1). doi: 10.1002/cbdv.201700343. Epub 2017 Dec 27. PubMed PMID: 29083533.
5: Kobaek-Larsen M, El-Houri RB, Christensen LP, Al-Najami I, Fretté X, Baatrup G. Dietary polyacetylenes, falcarinol and falcarindiol, isolated from carrots prevents the formation of neoplastic lesions in the colon of azoxymethane-induced rats. Food Funct. 2017 Mar 22;8(3):964-974. doi: 10.1039/c7fo00110j. PubMed PMID: 28197615.
