MI-223 is an inhibitor of Mcl-1-stimulated homologous recombination (HR) DNA repair, which leads to sensitization of cancer cells to hydroxyurea- or olaparib-induced DNA replication stress.
MedKoo Cat#: 564513
Name: MI-223
CAS#: 907166-59-0
Chemical Formula: C23H18ClN3O3
Exact Mass: 419.1037
Molecular Weight: 419.87
Elemental Analysis: C, 65.80; H, 4.32; Cl, 8.44; N, 10.01; O, 11.43
The following data is based on the product molecular weight 419.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
