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MedKoo Cat#: 584678 | Name: Maesaquinone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Maesaquinone is a novel inhibitor of plant mitochondrial respiratory enzymes that react with ubiquinone.

Chemical Structure

Maesaquinone
Maesaquinone
CAS#19833-20-6

Theoretical Analysis

MedKoo Cat#: 584678

Name: Maesaquinone

CAS#: 19833-20-6

Chemical Formula: C26H42O4

Exact Mass: 418.3083

Molecular Weight: 418.62

Elemental Analysis: C, 74.60; H, 10.11; O, 15.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Maesaquinone
IUPAC/Chemical Name
2-(14-Nonadecenyl)-3,6-dihydroxy-5-methyl-1,4-benzoquinone
InChi Key
UEFNZITZGVWLFK-VOTSOKGWSA-N
InChi Code
InChI=1S/C26H42O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-25(29)23(27)21(2)24(28)26(22)30/h6-7,27,30H,3-5,8-20H2,1-2H3/b7-6+
SMILES Code
O=C(C(C)=C1O)C(O)=C(CCCCCCCCCCCCC/C=C/CCCC)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 418.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: OGAWA H, NATORI S. HYDROXYBENZOQUINONES FROM MYRSINACEAE PLANTS. I. RECONFIRMATION OF THE STRUCTURE OF MAESAQUINONE AND ISOLATION OF ACETYLMAESAQUINONE FROM MAESA JAPONICA MORITZI. Chem Pharm Bull (Tokyo). 1965 Apr;13:511-6. PubMed PMID: 14294849. 2: Affourtit C, Whitehouse DG, Moore AL. Maesaquinone: a novel inhibitor of plant mitochondrial respiratory enzymes that react with ubiquinone. IUBMB Life. 2000 Jun;49(6):533-7. PubMed PMID: 11032248. 3: Makawiti DW, Konji VN, Olowookere JO. Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics. FEBS Lett. 1990 Jun 18;266(1-2):26-8. PubMed PMID: 2365068. 4: Han C, Wang L, Yu K, Chen L, Hu L, Chen K, Jiang H, Shen X. Biochemical characterization and inhibitor discovery of shikimate dehydrogenase from Helicobacter pylori. FEBS J. 2006 Oct;273(20):4682-92. Epub 2006 Sep 14. PubMed PMID: 16972983. 5: Affourtit C, Leach GR, Krab K, Moore AL. Kinetic interaction between oxidases and dehydrogenases in plant mitochondria. Biochem Soc Trans. 1997 Feb;25(1):60S. PubMed PMID: 9056958.