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MedKoo Cat#: 573164 | Name: Anisodine hydrobromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Anisodine hydrobromide is an anticholinergic which may have neuroprotective effects.

Chemical Structure

Anisodine hydrobromide
Anisodine hydrobromide
CAS#76822-34-9

Theoretical Analysis

MedKoo Cat#: 573164

Name: Anisodine hydrobromide

CAS#: 76822-34-9

Chemical Formula: C17H22BrNO5

Exact Mass: 399.0681

Molecular Weight: 400.27

Elemental Analysis: C, 51.01; H, 5.54; Br, 19.96; N, 3.50; O, 19.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Anisodine hydrobromide
IUPAC/Chemical Name
Benzeneacetic acid, alpha-hydroxy-alpha-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(sup 2,4))non-7-yl ester, hydrobromide, (7(S)-(1-alpha,2-beta,4-beta,5-alpha,7-beta))-
InChi Key
GJPDCORRBGIJOP-JYHRPVKFSA-N
InChi Code
1S/C17H21NO5.BrH/c1-18-12-7-11(8-13(18)15-14(12)23-15)22-16(20)17(21,9-19)10-5-3-2-4-6-10;/h2-6,11-15,19,21H,7-9H2,1H3;1H/t11-,12-,13+,14-,15+,17-;/m1./s1
SMILES Code
Br.CN1[C@H]2CC(C[C@@H]1[C@H]3O[C@@H]23)OC(=O)[C@@](O)(CO)c4ccccc4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 400.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen D, Peng C, Xie X, Chen Q, Liu H, Zhang S, Wan F, Ao H. Low Dose of Anisodine Hydrobromide Induced Neuroprotective Effects in Chronic Cerebral Hypoperfusion Rats. CNS Neurol Disord Drug Targets. 2017;16(10):1111-1119. doi: 10.2174/1871527316666171026114043. PubMed PMID: 29076436. 2: Wang Q, Gao S, Luo Y, Kang QY. Compound anisodine affects the proliferation and calcium overload of hypoxia-induced rat retinal progenitor cells and brain neural stem cells via the p-ERK1/2/HIF-1α/VEGF pathway. Exp Ther Med. 2017 Jul;14(1):600-608. doi: 10.3892/etm.2017.4528. Epub 2017 May 31. PubMed PMID: 28672973; PubMed Central PMCID: PMC5488403. 3: Liu WD, Chen LL, Shen CY, Jiang LB. Neuroprotective Effect of Compound Anisodine in a Mouse Model with Chronic Ocular Hypertension. Chin Med J (Engl). 2015 Oct 5;128(19):2652-7. doi: 10.4103/0366-6999.166043. PubMed PMID: 26415805; PubMed Central PMCID: PMC4736849. 4: Tian F, Li C, Wang X, Ren S, Li N, Liu Q, Zhou S, Lu Y, Zhao D, Chen X. Comparative study on pharmacokinetics of a series of anticholinergics, atropine, anisodamine, anisodine, scopolamine and tiotropium in rats. Eur J Drug Metab Pharmacokinet. 2015 Sep;40(3):245-53. doi: 10.1007/s13318-014-0192-y. Epub 2014 Apr 20. PubMed PMID: 24748278.