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MedKoo Cat#: 529190 | Name: LY-393615

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY-393615 is a neuronal calcium channel blocker.

Chemical Structure

LY-393615
LY-393615
CAS#325819-97-4

Theoretical Analysis

MedKoo Cat#: 529190

Name: LY-393615

CAS#: 325819-97-4

Chemical Formula: C21H26ClF2NO

Exact Mass: 381.1671

Molecular Weight: 381.89

Elemental Analysis: C, 66.05; H, 6.86; Cl, 9.28; F, 9.95; N, 3.67; O, 4.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LY-393615
IUPAC/Chemical Name
2-Furanmethanamine, n-butyl-5,5-bis(4-fluorophenyl)tetrahydro-, hydrochloride
InChi Key
GBBGQGHWUPHIOP-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H25F2NO.ClH/c1-2-3-14-24-15-20-12-13-21(25-20,16-4-8-18(22)9-5-16)17-6-10-19(23)11-7-17;/h4-11,20,24H,2-3,12-15H2,1H3;1H
SMILES Code
FC1=CC=C(C2(C3=CC=C(F)C=C3)CCC(CNCCCC)O2)C=C1.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 381.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: O'Neill MJ, Hicks CA, Ward MA, Osborne DJ, Wishart G, Mathews KS, McLaughlin DP, Stamford JA, McCarty DR, Patrick KE, Roman C, Fleisch JH, Gilmore J, Boot JR. LY393615, a novel neuronal Ca(2+) and Na(+) channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischemia. Brain Res. 2001 Jan 5;888(1):138-149. PubMed PMID: 11146060. 2: Hicks CA, Ward MA, O'Neill MJ. Neuroprotective effects of the neuronal Ca(2+) channel blockers, LY042826 and LY393615 in vivo. Eur J Pharmacol. 2000 Nov 24;408(3):241-8. PubMed PMID: 11090640.

View History

GT-2227

GT-2227