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MedKoo Cat#: 584663 | Name: Antibiotic M 14659

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Antibiotic M 14659 is an injectable semisynthetic cephalosporin.

Chemical Structure

Antibiotic M 14659
Antibiotic M 14659
CAS#114627-37-1

Theoretical Analysis

MedKoo Cat#: 584663

Name: Antibiotic M 14659

CAS#: 114627-37-1

Chemical Formula: C28H20N9Na3O11S3

Exact Mass: 823.0137

Molecular Weight: 823.67

Elemental Analysis: C, 40.83; H, 2.45; N, 15.31; Na, 8.37; O, 21.37; S, 11.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Antibiotic M 14659; M 14659; M14659
IUPAC/Chemical Name
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)((carboxy(3,4-dihydroxyphenyl)methoxy)imino)acetyl)amino)-3-(((2-carboxy-5-methyl(1,2,4)triazolo(1,5-a)pyrimidin-7-yl)thio)methyl)-8-oxo-, trisodium salt, (6R-(6alpha,7beta(Z(S*))))-
InChi Key
KKCORCGDIQPQOO-SNQWTNTOSA-K
InChi Code
InChI=1S/C28H23N9O11S3.3Na/c1-9-4-15(37-28(30-9)33-20(34-37)26(46)47)49-6-11-7-50-23-17(22(41)36(23)18(11)24(42)43)32-21(40)16(12-8-51-27(29)31-12)35-48-19(25(44)45)10-2-3-13(38)14(39)5-10;;;/h2-5,8,17,19,23,38-39H,6-7H2,1H3,(H2,29,31)(H,32,40)(H,42,43)(H,44,45)(H,46,47);;;/q;3*+1/p-3/b35-16-;;;/t17-,19+,23-;;;/m1.../s1
SMILES Code
O=C(C(N12)=C(CSC3=CC(C)=NC4=NC(C([O-])=O)=NN34)CS[C@]2([H])[C@H](NC(/C(C5=CSC(N)=N5)=N\O[C@H](C([O-])=O)C6=CC=C(O)C(O)=C6)=O)C1=O)[O-].[Na+].[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 823.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mochizuki H, Yamada H, Oikawa Y, Murakami K, Ishiguro J, Kosuzume H, Aizawa N, Mochida E. Bactericidal activity of M14659 enhanced in low-iron environments. Antimicrob Agents Chemother. 1988 Nov;32(11):1648-54. PubMed PMID: 2978112; PubMed Central PMCID: PMC175946. 2: Mochizuki H, Oikawa Y, Yamada H, Kusakabe S, Shiihara T, Murakami K, Kato K, Ishiguro J, Kosuzume H. Antibacterial and pharmacokinetic properties of M14659, a new injectable semisynthetic cephalosporin. J Antibiot (Tokyo). 1988 Mar;41(3):377-91. PubMed PMID: 3130365.