MedKoo Cat#: 573150 | Name: Octopamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Octopamine is an alpha-adrenergic sympathomimetic amine biosynthesized from tyramine. Octopamine may be found in the CNS, platelets, and in invertebrate nervous systems. It is used to treat hypotension and may acy as a cardiotonic.

Chemical Structure

Octopamine
Octopamine
CAS#104-14-3

Theoretical Analysis

MedKoo Cat#: 573150

Name: Octopamine

CAS#: 104-14-3

Chemical Formula: C8H11NO2

Exact Mass: 153.0790

Molecular Weight: 153.18

Elemental Analysis: C, 62.73; H, 7.24; N, 9.14; O, 20.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Analet, ND 50, Norden, Norfen, Norphen, Norsympathol, Norsympatol, Norsynephrine, Octopamine, Paraoxyphenyl aminoethanol
IUPAC/Chemical Name
Benzenemethanol, alpha-(aminomethyl)-4-hydroxy-
InChi Key
QHGUCRYDKWKLMG-UHFFFAOYSA-N
InChi Code
1S/C8H11NO2/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8,10-11H,5,9H2
SMILES Code
c1(ccc(O)cc1)[C@@H](CN)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.

Preparing Stock Solutions

The following data is based on the product molecular weight 153.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Li Y, Hoffmann J, Li Y, Stephano F, Bruchhaus I, Fink C, Roeder T. Octopamine controls starvation resistance, life span and metabolic traits in Drosophila. Sci Rep. 2016 Oct 19;6:35359. doi: 10.1038/srep35359. PubMed PMID: 27759117; PubMed Central PMCID: PMC5069482. 2: Money TG, Sproule MK, Cross KP, Robertson RM. Octopamine stabilizes conduction reliability of an unmyelinated axon during hypoxic stress. J Neurophysiol. 2016 Sep 1;116(3):949-59. doi: 10.1152/jn.00354.2016. Epub 2016 Jun 8. PubMed PMID: 27281750; PubMed Central PMCID: PMC5009204. 3: Furuhashi T, Sakamoto K. Central nervous system promotes thermotolerance via FoxO/DAF-16 activation through octopamine and acetylcholine signaling in Caenorhabditis elegans. Biochem Biophys Res Commun. 2016 Mar 25;472(1):114-7. doi: 10.1016/j.bbrc.2016.02.076. Epub 2016 Feb 20. PubMed PMID: 26903298. 4: Yang Z, Yu Y, Zhang V, Tian Y, Qi W, Wang L. Octopamine mediates starvation-induced hyperactivity in adult Drosophila. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5219-24. doi: 10.1073/pnas.1417838112. Epub 2015 Apr 6. PubMed PMID: 25848004; PubMed Central PMCID: PMC4413307. 5: Stohs SJ. Physiological functions and pharmacological and toxicological effects of p-octopamine. Drug Chem Toxicol. 2015 Jan;38(1):106-12. doi: 10.3109/01480545.2014.900069. Epub 2014 Mar 24. Review. PubMed PMID: 24654910.