MedKoo Cat#: 528094 | Name: 4-(Beta-aminoethyl)thiazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

4-(Beta-aminoethyl)thiazole is a histamine analog which can induce cross-tolerance to histamine.

Chemical Structure

4-(Beta-aminoethyl)thiazole
4-(Beta-aminoethyl)thiazole
CAS#7728-74-7

Theoretical Analysis

MedKoo Cat#: 528094

Name: 4-(Beta-aminoethyl)thiazole

CAS#: 7728-74-7

Chemical Formula: C5H10Cl2N2S

Exact Mass: 199.9942

Molecular Weight: 201.11

Elemental Analysis: C, 29.86; H, 5.01; Cl, 35.25; N, 13.93; S, 15.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
4-(Beta-aminoethyl)thiazole
IUPAC/Chemical Name
4-Thiazoleethanamine, dihydrochloride
InChi Key
WNBVPHXGUOQHFD-UHFFFAOYSA-N
InChi Code
InChI=1S/C5H8N2S.2ClH/c6-2-1-5-3-8-4-7-5;;/h3-4H,1-2,6H2;2*1H
SMILES Code
NCCC1=CSC=N1.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 201.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ionov M, Gordiyenko NV, Zukowska I, Tokhtaeva E, Mareninova OA, Baram N, Ziyaev K, Rezhepov K, Zamaraeva M. Stability and antioxidant activity of gossypol derivative immobilized on N-polyvinylpyrrolidone. Int J Biol Macromol. 2012 Dec;51(5):908-14. doi: 10.1016/j.ijbiomac.2012.08.005. Epub 2012 Aug 10. PubMed PMID: 22910577. 2: Sobolev AS, Chirkov YuYu, Tertov VV, Kazarov AR. Effects of radioprotectors on the cAMP and cGMP systems. Radiat Environ Biophys. 1984;23(2):79-93. PubMed PMID: 6146160. 3: Goncharenko EN, Stoev SV, Antonova SV, Graevskaia EE. [Role of endogenous substances in creating a background of increased radioresistance. 16. Effect of AET derivatives on the endogenous background of radioresistance]. Radiobiologiia. 1982 Mar-Apr;22(2):252-5. Russian. PubMed PMID: 7115547. 4: Rónai E, Benkö G, Perjés I, Szabó DL. [Quantitative determination of the ratio of 2-aminothiazoline contamination in IXECUR enteric-coated dragees]. Acta Pharm Hung. 1981 Jul;51(4):173-6. Hungarian. PubMed PMID: 7293786. 5: Anwar AR, Kay AB. H1-receptor dependence of histamine-induced enhancement of human eosinophil C3b rosettes. Clin Exp Immunol. 1980 Oct;42(1):196-9. PubMed PMID: 6109584; PubMed Central PMCID: PMC1537069. 6: DILLEY J, DOULL J. PHARMACOLOGICAL AND TOXICOLOGICAL COMPOUNDS AS PROTECTIVE OR THERAPEUTIC AGENTS AGAINST RADIATION INJURY IN EXPERIMENTAL ANIMALS. I. EFFECTS OF 2-IMINO-THIAZOLIDINE-4-CARBOXYLIC ACID ON THE RADIOPROTECTIVE ACTIVITY OF VARIOUS CHEMICAL AGENTS. REP NO. 51. Q Prog Rep United States Air Force Radiat Lab Univ Chic. 1964 Apr 15;51:42-57. PubMed PMID: 14150450. 7: ZAPADNIUK VI. [Pharmacological studies on 3(-beta-aminoethyl)-2,4-thiazolidinedione hydrochloride]. Farmakol Toksikol. 1961 Nov-Dec;24:665-70. Russian. PubMed PMID: 14009835.