MedKoo Cat#: 564407 | Name: MAO-B inhibitor C5

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MAO-B inhibitor C5 is a potent and selective MAO-B inhibitor.

Chemical Structure

MAO-B inhibitor C5
MAO-B inhibitor C5
CAS#1230-77-9

Theoretical Analysis

MedKoo Cat#: 564407

Name: MAO-B inhibitor C5

CAS#: 1230-77-9

Chemical Formula: C18H19NO2

Exact Mass: 281.1416

Molecular Weight: 281.36

Elemental Analysis: C, 76.84; H, 6.81; N, 4.98; O, 11.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
MAO-B inhibitor C-5; MAO-B inhibitor-C5; MAO-B inhibitor C5
IUPAC/Chemical Name
(2E)-3-[4-(Dimethylamino) phenyl]-1-(4-methoxyphenyl) prop-2-en-1-one
InChi Key
VYCHTZRFUNDXSN-AWNIVKPZSA-N
InChi Code
InChI=1S/C18H19NO2/c1-19(2)16-9-4-14(5-10-16)6-13-18(20)15-7-11-17(21-3)12-8-15/h4-13H,1-3H3/b13-6+
SMILES Code
O=C(C1=CC=C(OC)C=C1)/C=C/C2=CC=C(N(C)C)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 281.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mathew B, Mathew GE, Ucar G, Joy M, Nafna EK, Lohidakshan KK, Suresh J. Monoamine oxidase inhibitory activity of methoxy-substituted chalcones. Int J Biol Macromol. 2017 Nov;104(Pt A):1321-1329. doi: 10.1016/j.ijbiomac.2017.05.162. Epub 2017 Jun 1. PubMed PMID: 28577983. 2: Zarmouh NO, Messeha SS, Elshami FM, Soliman KF. Evaluation of the Isoflavone Genistein as Reversible Human Monoamine Oxidase-A and -B Inhibitor. Evid Based Complement Alternat Med. 2016;2016:1423052. doi: 10.1155/2016/1423052. Epub 2016 Mar 28. PubMed PMID: 27118978; PubMed Central PMCID: PMC4826920. 3: Mostert S, Petzer A, Petzer JP. Indanones as high-potency reversible inhibitors of monoamine oxidase. ChemMedChem. 2015 May;10(5):862-73. doi: 10.1002/cmdc.201500059. Epub 2015 Mar 27. PubMed PMID: 25820651.