MedKoo Cat#: 564398 | Name: Desmethyl-HD-800

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Desmethyl-HD-800 is a PET precursor of preparing radiolabel [11C]HD-800, a high affinity brain penetrant PET tracer for imaging microtubules.

Chemical Structure

Desmethyl-HD-800
Desmethyl-HD-800
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564398

Name: Desmethyl-HD-800

CAS#: NONE

Chemical Formula: C14H13N3O2

Exact Mass: 255.1008

Molecular Weight: 255.28

Elemental Analysis: C, 65.87; H, 5.13; N, 16.46; O, 12.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Desmethyl-HD-800; Desmethyl-HD800; Desmethyl HD800
IUPAC/Chemical Name
4-(Methyl(5-methylfuro[2,3-d]pyrimidin-4-yl)amino)phenol
InChi Key
BFHWLLKPJGZILN-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H13N3O2/c1-9-7-19-14-12(9)13(15-8-16-14)17(2)10-3-5-11(18)6-4-10/h3-8,18H,1-2H3
SMILES Code
OC1=CC=C(N(C)C2=C3C(OC=C3C)=NC=N2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 255.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Solingapuram Sai KK, Prabhakaran J, Ramanathan G, Rideout S, Whitlow C, Mintz A, Mann JJ, Kumar JSD. Radiosynthesis and Evaluation of [(11)C]HD-800, a High Affinity Brain Penetrant PET Tracer for Imaging Microtubules. ACS Med Chem Lett. 2018 Apr 30;9(5):452-456. doi: 10.1021/acsmedchemlett.8b00060. eCollection 2018 May 10. PubMed PMID: 29795758; PubMed Central PMCID: PMC5949725.