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MedKoo Cat#: 581558 | Name: Melianol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Melianol is a natural compound in the fruits of Melia azeradacha. It has potent antiviral activity (EC50 in the range of 3-11μM) against human pathogens. They are known as cytotoxic compounds against different cancer cell lines.

Chemical Structure

Melianol
Melianol
CAS#16838-01-0

Theoretical Analysis

MedKoo Cat#: 581558

Name: Melianol

CAS#: 16838-01-0

Chemical Formula: C30H48O4

Exact Mass: 472.3553

Molecular Weight: 472.71

Elemental Analysis: C, 76.23; H, 10.24; O, 13.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Melianol; Deacetylturreanthin;
IUPAC/Chemical Name
13a,14b,17bH-Lanost-7-ene-3b,21-diol, 21,23:24,25-diepoxy-
InChi Key
DABHSVCBZNIZDT-QXEWJOEMSA-N
InChi Code
InChI=1S/C30H48O4/c1-26(2)22-9-8-20-19(28(22,5)13-12-23(26)31)11-15-29(6)18(10-14-30(20,29)7)17-16-21(33-25(17)32)24-27(3,4)34-24/h8,17-19,21-25,31-32H,9-16H2,1-7H3/t17-,18-,19+,21?,22+,23+,24?,25?,28-,29+,30-/m1/s1
SMILES Code
CC1(C)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC[C@@]4(C)[C@@H]([C@H](C(O5)O)CC5C(O6)C6(C)C)CC[C@@](C)4C3=CC[C@@]12[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 472.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sanna G, Madeddu S, Giliberti G, Ntalli NG, Cottiglia F, De Logu A, Agus E, Caboni P. Limonoids from Melia azedarach Fruits as Inhibitors of Flaviviruses and Mycobacterium tubercolosis. PLoS One. 2015 Oct 20;10(10):e0141272. doi: 10.1371/journal.pone.0141272. eCollection 2015. PubMed PMID: 26485025; PubMed Central PMCID: PMC4612778. 2: Miguita CH, Barbosa Cda S, Hamerski L, Sarmento UC, Nascimento JN, Garcez WS, Garcez FR. 3β-O-tigloylmelianol from Guarea kunthiana: a new potential agent to control Rhipicephalus (Boophilus) microplus, a cattle tick of veterinary significance. Molecules. 2014 Dec 23;20(1):111-26. doi: 10.3390/molecules20010111. PubMed PMID: 25546624. 3: Han J, Lin WH, Xu RS, Wang WL, Zhao SH. [Studies on the chemical constituents of Melia azedarach L]. Yao Xue Xue Bao. 1991;26(6):426-9. Chinese. PubMed PMID: 1789108.