MedKoo Cat#: 564352 | Name: ARN726
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ARN726 is a systemically active N-acylethanolamine acid amidase (NAAA) inhibitor.

Chemical Structure

ARN726
ARN726
CAS#1628343-77-0

Theoretical Analysis

MedKoo Cat#: 564352

Name: ARN726

CAS#: 1628343-77-0

Chemical Formula: C14H24N2O3

Exact Mass: 268.1787

Molecular Weight: 268.36

Elemental Analysis: C, 62.66; H, 9.01; N, 10.44; O, 17.89

Price and Availability

Size Price Availability Quantity
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
200mg USD 1,950.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,950.00 2 Weeks
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Related CAS #
No Data
Synonym
ARN0726; ARN-0726; ARN 0726; ARN-726; ARN 726; ARN726
IUPAC/Chemical Name
4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]-carbamate
InChi Key
FNLUJRBWJBUJTC-LBPRGKRZSA-N
InChi Code
InChI=1S/C14H24N2O3/c17-13-12(10-15-13)16-14(18)19-9-5-4-8-11-6-2-1-3-7-11/h11-12H,1-10H2,(H,15,17)(H,16,18)/t12-/m0/s1
SMILES Code
O=C(OCCCCC1CCCCC1)N[C@@H]2C(NC2)=O
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 268.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bonezzi FT, Sasso O, Pontis S, Realini N, Romeo E, Ponzano S, Nuzzi A, Fiasella A, Bertozzi F, Piomelli D. An Important Role for N-Acylethanolamine Acid Amidase in the Complete Freund's Adjuvant Rat Model of Arthritis. J Pharmacol Exp Ther. 2016 Mar;356(3):656-63. doi: 10.1124/jpet.115.230516. Epub 2016 Jan 14. PubMed PMID: 26769918. 2: Romeo E, Ponzano S, Armirotti A, Summa M, Bertozzi F, Garau G, Bandiera T, Piomelli D. Activity-Based Probe for N-Acylethanolamine Acid Amidase. ACS Chem Biol. 2015 Sep 18;10(9):2057-2064. doi: 10.1021/acschembio.5b00197. Epub 2015 Jun 23. PubMed PMID: 26102511; PubMed Central PMCID: PMC4575644.