PK5196 is a potent ligand to target the Y220C pocket, stabilizing Y220C. PK5196 displays a Kd of 10 μM and raises the Tm of the protein by almost 4 °C under saturating conditions.
MedKoo Cat#: 564329
Name: PK5196
CAS#: 1370554-91-8
Chemical Formula: C25H32IN3O
Exact Mass: 517.1590
Molecular Weight: 517.46
Elemental Analysis: C, 58.03; H, 6.23; I, 24.52; N, 8.12; O, 3.09
The following data is based on the product molecular weight 517.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
