SKLB050 is a derivative of millepachine (MIL), which is a natural chalcone-type small molecule extracted from the plant Millettia pachycarpa. SKLB050 has potential antitumor activities both in vitro and in vivo. Biochemical and cellular experiments reveal that SKLB050 directly and irreversibly binds β-tubulin.
MedKoo Cat#: 564319
Name: SKLB050
CAS#: NONE
Chemical Formula: C22H23NO4
Exact Mass: 365.1627
Molecular Weight: 365.43
Elemental Analysis: C, 72.31; H, 6.34; N, 3.83; O, 17.51
The following data is based on the product molecular weight 365.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
