Acetylcarnitine arginyl amide | CAS# 149341-40-2| Neurite Outgrowth Factor

MedKoo Cat#: 573096 | Name: Acetylcarnitine arginyl amide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Acetylcarnitine arginyl amide is able to stimulate neurite outgrowth in a manner similar to that elicited by nerve growth factor (NGF). Neurite induction by this molecule requires de novo mRNA synthesis and is independent of the action of several common trophic factors.

Chemical Structure

Acetylcarnitine arginyl amide

CAS#149341-40-2

Theoretical Analysis

MedKoo Cat#: 573096

Name: Acetylcarnitine arginyl amide

CAS#: 149341-40-2

Chemical Formula: C15H30N5O5

Exact Mass: 360.2241

Molecular Weight: 360.43

Elemental Analysis: C, 49.99; H, 8.39; N, 19.43; O, 22.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Acetylcarnitine arginyl amide, acetyl-L-carnitine arginine amide, ST-857

IUPAC/Chemical Name

1-Butanaminium, 2-(acetyloxy)-4-((4-((aminoiminomethyl)amino)-1-carboxybutyl)amino)-N,N,N-trimethyl-4-oxo-, (R,(R*,S*))-

InChi Key

TYAKLKJKQKTTMI-NEPJUHHUSA-O

InChi Code

1S/C15H29N5O5/c1-10(21)25-11(9-20(2,3)4)8-13(22)19-12(14(23)24)6-5-7-18-15(16)17/h11-12H,5-9H2,1-4H3,(H5-,16,17,18,19,22,23,24)/p+1/t11-,12+/m1/s1

SMILES Code

NC(NCCC[C@@H](C(O)=O)NC(C[C@H](C[N+](C)(C)C)OC(C)=O)=O)=N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 360.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Scorziello A, Meucci O, Calvani M, Schettini G. Acetyl-L-carnitine arginine amide prevents beta 25-35-induced neurotoxicity in cerebellar granule cells. Neurochem Res. 1997 Mar;22(3):257-65. PubMed PMID: 9051659. 2: Taglialatela G, Navarra D, Olivi A, Ramacci MT, Werrbach-Perez K, Perez-Polo JR, Angelucci L. Neurite outgrowth in PC12 cells stimulated by acetyl-L-carnitine arginine amide. Neurochem Res. 1995 Jan;20(1):1-9. PubMed PMID: 7739750. 3: Westlund KN, Lu Y, Werrbach-Perez K, Hulsebosch CE, Morgan B, Pizzo DP, Eisenberg HM, Perez-Polo JR. Effects of nerve growth factor and acetyl-L-carnitine arginyl amide on the human neuronal line HCN-1A. Int J Dev Neurosci. 1992 Oct;10(5):361-73. PubMed PMID: 1283485.