Quifenadine | CAS# 10447-39-9 | H1-histamine Receptor Blocker

MedKoo Cat#: 564068 | Name: Quifenadine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quifenadine is an H1-histamine receptor blocker with antiarrhythmic properties.

Chemical Structure

Quifenadine

CAS#10447-39-9

Theoretical Analysis

MedKoo Cat#: 564068

Name: Quifenadine

CAS#: 10447-39-9

Chemical Formula: C20H23NO

Exact Mass: 293.1780

Molecular Weight: 293.41

Elemental Analysis: C, 81.87; H, 7.90; N, 4.77; O, 5.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Phencarol; Fenatin; Fencarol; Quifenadine

IUPAC/Chemical Name

1-Azabicyclo[2.2.2]octan-3-yl(diphenyl)methanol

InChi Key

PZMAHNDJABQWGS-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H23NO/c22-20(17-7-3-1-4-8-17,18-9-5-2-6-10-18)19-15-21-13-11-16(19)12-14-21/h1-10,16,19,22H,11-15H2

SMILES Code

OC(C1=CC=CC=C1)(C2CN3CCC2CC3)C4=CC=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 293.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Luss LV. [Use of antihistamines in a physician's clinical practice]. Ter Arkh. 2014;86(8):106-9. Review. Russian. PubMed PMID: 25306755. 2: Makarov L, Balykova L, Soldatova O, Komolyatova V, Serebruany V. The antiarrhythmic properties of quifenadine, H1-histamine receptor blocker in children with premature beats: a randomized controlled pilot trial. Am J Ther. 2010 Jul-Aug;17(4):396-401. doi: 10.1097/MJT.0b013e3181a86987. PubMed PMID: 19487925. 3: Ismailov SR. [Effect of phencarol on pancreatic digestive enzymes in food anaphylaxis]. Eksp Klin Farmakol. 2001 May-Jun;64(3):48-9. Russian. PubMed PMID: 11558439. 4: Galenko Iaroshevskiĭ PA, Cherednik IL, Bartashevich VV, Sheĭkh-Zade IuR, Khankoeva AI. [Comparative evaluation of the anti-arrhythmia efficacy of fencarol and dimebon during neurogenic atrial fibrillation]. Biull Eksp Biol Med. 1997 Jul;124(7):81-5. Russian. PubMed PMID: 9303740. 5: Iakovlev GM, Skorobogatov VI, Svistov AS, Mironova MI. [The experimental anti-arrhythmia properties of the histamine H1 receptor blockader fencarol]. Farmakol Toksikol. 1991 Sep-Oct;54(5):25-7. Russian. PubMed PMID: 1686869.