Amiodarone is an effective antiarrhythmic drug handicapped by serious side effects. The mechanism of its antiarrhythmic activity is not known but is presumed to involve inhibition of current flowing through ion channels. Des-oxo-amiodarone, a close structural analogue of amiodarone, blocks cardiac ion channels.
MedKoo Cat#: 581385
Name: Desoxoamiodrone
CAS#: 116523-57-0
Chemical Formula: C25H31I2NO2
Exact Mass: 631.0444
Molecular Weight: 631.34
Elemental Analysis: C, 47.56; H, 4.95; I, 40.20; N, 2.22; O, 5.07
The following data is based on the product molecular weight 631.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
