MedKoo Cat#: 584577 | Name: Sulukast

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulukast leukotriene D4 and E4 antagonist in the guinea-pig and anti-asthmatic.

Chemical Structure

Sulukast
Sulukast
CAS#98116-53-1

Theoretical Analysis

MedKoo Cat#: 584577

Name: Sulukast

CAS#: 98116-53-1

Chemical Formula: C25H36N4O3S

Exact Mass: 472.2508

Molecular Weight: 472.65

Elemental Analysis: C, 63.53; H, 7.68; N, 11.85; O, 10.15; S, 6.78

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sulukast; LY 170680; LY170680; LY-170680
IUPAC/Chemical Name
Propanoic acid, 3-((1-(hydroxy(3-(1H-tetrazol-5-yl)phenyl)methyl)-2,4-tetradecadienyl)thio)-, (R-(R*,S*-(E,Z)))-
InChi Key
YPHOSUPSOWQQCB-AFOLHBCXSA-N
InChi Code
InChI=1S/C25H36N4O3S/c1-2-3-4-5-6-7-8-9-10-11-12-16-22(33-18-17-23(30)31)24(32)20-14-13-15-21(19-20)25-26-28-29-27-25/h10-16,19,22,24,32H,2-9,17-18H2,1H3,(H,30,31)(H,26,27,28,29)/b11-10-,16-12+/t22-,24+/m1/s1
SMILES Code
O=C(O)CCS[C@@H]([C@@H](O)C1=CC=CC(C2=NN=NN2)=C1)/C=C/C=C\CCCCCCCCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 472.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Boot JR, Bond A, Gooderham R, O'Brien A, Parsons M, Thomas KH. The pharmacological evaluation of LY 170680, a novel leukotriene D4 and E4 antagonist in the guinea-pig. Br J Pharmacol. 1989 Sep;98(1):259-67. PubMed PMID: 2553189; PubMed Central PMCID: PMC1854672. 2: Fish BJ. Use of a porous graphitic carbon column to separate cis and trans isomers in a novel anti-asthma compound. J Pharm Biomed Anal. 1993 Jun;11(6):517-21. PubMed PMID: 8399524.