Synonym
7-O-(Amino-PEG4)- paclitaxel
IUPAC/Chemical Name
(2aR,4S,4aS,6R,9S,11S,12S,12bS)-4-((1-amino-3,6,9,12-tetraoxapentadecan-15-oyl)oxy)-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate
InChi Key
VDNLACHAGAYEKT-QFWHBDSMSA-N
InChi Code
InChI=1S/C58H72N2O19/c1-35-41(76-54(68)47(64)46(38-16-10-7-11-17-38)60-52(66)39-18-12-8-13-19-39)33-58(69)51(78-53(67)40-20-14-9-15-21-40)49-56(6,50(65)48(75-36(2)61)45(35)55(58,4)5)42(32-43-57(49,34-74-43)79-37(3)62)77-44(63)22-24-70-26-28-72-30-31-73-29-27-71-25-23-59/h7-21,41-43,46-49,51,64,69H,22-34,59H2,1-6H3,(H,60,66)/t41-,42-,43+,46-,47+,48+,49?,51-,56+,57-,58+/m0/s1
SMILES Code
O=C(C1=CC=CC=C1)N[C@H]([C@@H](O)C(O[C@H]2C[C@]([C@H]3OC(C4=CC=CC=C4)=O)(O)C(C)(C)C([C@H](C([C@@]5(C)C3[C@@](CO6)(OC(C)=O)[C@H]6C[C@@H]5OC(CCOCCOCCOCCOCCN)=O)=O)OC(C)=O)=C2C)=O)C7=CC=CC=C7
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
