Brosuximide | CAS#22855-57-8 | antiepileptic

MedKoo Cat#: 584566 | Name: Brosuximide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Brosuximide is an antiepileptic drug.

Chemical Structure

Brosuximide

CAS#22855-57-8

Theoretical Analysis

MedKoo Cat#: 584566

Name: Brosuximide

CAS#: 22855-57-8

Chemical Formula: C10H8BrNO2

Exact Mass: 252.9738

Molecular Weight: 254.08

Elemental Analysis: C, 47.27; H, 3.17; Br, 31.45; N, 5.51; O, 12.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Brosuximide; Lefadol; 3-Bromophenylsuccinimide

IUPAC/Chemical Name

2,5-Pyrrolidinedione, 3-(3-bromophenyl)- (9CI)

InChi Key

UTVDIOAGFGTMTM-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H8BrNO2/c11-7-3-1-2-6(4-7)8-5-9(13)12-10(8)14/h1-4,8H,5H2,(H,12,13,14)

SMILES Code

O=C(C(C1=CC=CC(Br)=C1)C2)NC2=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 254.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Czuczwar SJ, Turski L, Turski W, Kleinrok Z. Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid. Epilepsia. 1981 Aug;22(4):407-14. PubMed PMID: 6790272. 2: Kleinrok Z, Sieklucka-Dziuba M, Chodkowska A. [Comparison of the anticonvulsant and central effects of 3-bromophenylsuccinimide and N-methylimide of 3,5-dibromophenylsuccinic acid]. Acta Pol Pharm. 1982;39(5-6):475-82. Polish. PubMed PMID: 6927301. 3: Wójcik A. [Comparison of the anticonvulsive action of lefadol and 3-bromophenylsuccinimide and their effect on neuromediator levels in the brain]. Acta Pol Pharm. 1983;40(5-6):657-67. Polish. PubMed PMID: 6145296. 4: Wójcik A. [Comparison of the central effect of lefadol and 3-bromophenylsuccinimide]. Acta Pol Pharm. 1983;40(5-6):669-79. Polish. PubMed PMID: 6677072. 5: Kleinrok Z, Czuczwar SJ, Turski L. Prevention of kainic acid-induced seizure-like activity by antiepileptic drugs. Pol J Pharmacol Pharm. 1980 May-Jun;32(3):261-9. PubMed PMID: 6792611.