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MedKoo Cat#: 564010 | Name: Dooku1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dooku1 is a Yoda1 analogue. Dooku1 antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation..

Chemical Structure

Dooku1
Dooku1
CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564010

Name: Dooku1

CAS#: NONE

Chemical Formula: C13H9Cl2N3OS

Exact Mass: 324.9843

Molecular Weight: 326.20

Elemental Analysis: C, 47.87; H, 2.78; Cl, 21.74; N, 12.88; O, 4.90; S, 9.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Dooku1, Dooku-1, Dooku 1
IUPAC/Chemical Name
2-((2,6-Dichlorobenzyl)thio)-5-(1H-pyrrol-2-yl)-1,3,4-oxadiazole
InChi Key
MNPOBXLPCWFONX-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H9Cl2N3OS/c14-9-3-1-4-10(15)8(9)7-20-13-18-17-12(19-13)11-5-2-6-16-11/h1-6,16H,7H2
SMILES Code
ClC1=C(C(Cl)=CC=C1)CSC2=NN=C(C3=CC=CN3)O2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 326.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Evans EL, Cuthbertson K, Endesh N, Rode B, Blythe NM, Hyman AJ, Hall SJ, Gaunt HJ, Ludlow MJ, Foster R, Beech DJ. Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation. Br J Pharmacol. 2018 May;175(10):1744-1759. doi: 10.1111/bph.14188. Epub 2018 Apr 6. PubMed PMID: 29498036; PubMed Central PMCID: PMC5913400.