MedKoo Cat#: 341385 | Name: Mexacarbate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mexacarbate is a carbamate pesticide developed by Alexander Shulgin.

Chemical Structure

Mexacarbate
Mexacarbate
CAS#315-18-4

Theoretical Analysis

MedKoo Cat#: 341385

Name: Mexacarbate

CAS#: 315-18-4

Chemical Formula: C12H18N2O2

Exact Mass: 222.1368

Molecular Weight: 222.29

Elemental Analysis: C, 64.84; H, 8.16; N, 12.60; O, 14.39

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Synonym
Mexacarbate; OMS 639; OMS-639; OMS639.
IUPAC/Chemical Name
4-(Dimethylamino)-3,5-xylyl methylcarbamate
InChi Key
YNEVBPNZHBAYOA-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H18N2O2/c1-8-6-10(16-12(15)13-3)7-9(2)11(8)14(4)5/h6-7H,1-5H3,(H,13,15)
SMILES Code
O=C(OC1=CC(C)=C(N(C)C)C(C)=C1)NC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Biological target:
Mexacarbate is a carbamate pesticide developed by Alexander Shulgin.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 222.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Singh A, Singh DK, Agarwal RA. Effect of cypermethrin, mexacarbate, and phorate on phospholipid and lipid peroxidation in the snail Lymnaea acuminata. Bull Environ Contam Toxicol. 1993 Jul;51(1):68-71. PubMed PMID: 8318776. 2: Fleming RA, Holmes SB, Busby DG. An interlaboratory comparison of data on brain cholinesterase activity in forest songbirds exposed to aerial application of Zectran. Arch Environ Contam Toxicol. 1992 Feb;22(2):228-37. PubMed PMID: 1536602. 3: Busby DG, Holmes SB, Pearce PA, Fleming RA. The effect of aerial application of Zectran on brain cholinesterase activity in forest songbirds. Arch Environ Contam Toxicol. 1987 Sep;16(5):623-9. PubMed PMID: 3632045. 4: Edmiston CE Jr, Goheen M, Malaney GW, Mills WL. Evaluation of carbamate toxicity: acute toxicity in a culture of Paramecium multimicronucleatum upon exposure to aldicarb, carbaryl, and mexacarbate as measured by Warburg respirometry and acute plate assay. Environ Res. 1985 Apr;36(2):338-50. PubMed PMID: 3920045. 5: Singh DK, Agarwal RA. Inhibition kinetics of certain organophosphorus and carbamate pesticides on acetylcholinesterase from the snail Lymnaea acuminata. Toxicol Lett. 1983 Dec;19(3):313-9. PubMed PMID: 6658844. 6: Gooch JW, Matsumura F. Characteristics of the hepatic monooxygenase system of the goldfish (Carassius auratus) and its induction with beta-naphthoflavone. Toxicol Appl Pharmacol. 1983 May;68(3):380-91. PubMed PMID: 6857672. 7: Szeto SY, Sundaram KM. Simplified method for the analysis of some carbamate insecticides in foliage, forest soil and fish tissue by direct gas-liquid chromatography. J Chromatogr. 1980 Nov 21;200:179-84. PubMed PMID: 7451606. 8: Sundaram KM, Szeto SY, Hindle R. Evaluation of Amberlite XAD-2 as the extractant for carbamate insecticides from natural water. J Chromatogr. 1979 Sep 14;177(1):29-34. PubMed PMID: 536444. 9: National Toxicology Program. Bioassay of mexacarbate for possible carcinogenicity. Natl Cancer Inst Carcinog Tech Rep Ser. 1978;147:1-107. PubMed PMID: 12799715. 10: Mauck WL, Olson LE, Hogan JW. Effects of water quality on deactivation and toxicity of mexacarbate (Zectran) to fish. Arch Environ Contam Toxicol. 1977;6(4):385-93. PubMed PMID: 318533. 11: Sheridan RP, Simms MA. Effects of the insecticide Zectran (Mexacarbate) on several algae. Bull Environ Contam Toxicol. 1975 May;13(5):565-9. PubMed PMID: 1148411. 12: Benezet HJ, Matsumura F. Factors influencing the metabolism of mexacarbate by microorganisms. J Agric Food Chem. 1974 May-Jun;22(3):427-30. PubMed PMID: 4840505. 13: GEORGHIOU GP, GARBER MJ. STUDIES ON THE INHERITANCE OF CARBAMATE-RESISTANCE IN THE HOUSEFLY (MUSCA DOMESTICA L.). Bull World Health Organ. 1965;32:181-96. PubMed PMID: 14310905; PubMed Central PMCID: PMC2555223.