DDE | CAS#72-55-9 | pesticide

MedKoo Cat#: 581342 | Name: DDE

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DDE is also know as 4,4’-DDE. It is a metabolite of DDT (D434195), a synthetic organochlorine insecticide that functions by opening sodium ion channels in the insects’ neurons, causing them to fire spontaneously which in turn leads to death. 4,4’-DDE has shown to have endocrine disrupting effects on gonadotropin hormones in pituitary gonadotrope cells.

Chemical Structure

DDE

CAS#72-55-9

Theoretical Analysis

MedKoo Cat#: 581342

Name: DDE

CAS#: 72-55-9

Chemical Formula: C14H8Cl4

Exact Mass: 315.9380

Molecular Weight: 318.02

Elemental Analysis: C, 52.88; H, 2.54; Cl, 44.59

Price and Availability

Size	Price	Availability
100mg	USD 250.00	2 Weeks
200mg	USD 350.00	2 Weeks
500mg	USD 550.00	2 Weeks

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Related CAS #

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Synonym

DDE; DDT dehydrochloride; 4,4'-DDE; p,p'-DDE; NSC 1153; NSC1153; NSC-1153;

IUPAC/Chemical Name

1,1'-(Dichloroethenylidene)bis(4-chlorobenzene)

InChi Key

UCNVFOCBFJOQAL-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H8Cl4/c15-11-5-1-9(2-6-11)13(14(17)18)10-3-7-12(16)8-4-10/h1-8H

SMILES Code

Cl/C(Cl)=C(C1=CC=C(Cl)C=C1)/C2=CC=C(Cl)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 318.02 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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Past and recent state of sediment contamination by persistent organic pollutants (POPs) in the Rhône River: Overview of ecotoxicological implications. Sci Total Environ. 2019 Jan 1;646:1037-1046. doi: 10.1016/j.scitotenv.2018.07.340. Epub 2018 Jul 25. PubMed PMID: 30235589. 5: Zhou Y, Chen J, Hu B, Cao S, Zhou Q, Guo R. The predictive value of intra-left atrial mechanical delay for 1-year recurrence of atrial fibrillation after catheter ablation: A clinical follow-up study using dual Doppler echocardiography. J Clin Ultrasound. 2018 Sep 19. doi: 10.1002/jcu.22629. [Epub ahead of print] PubMed PMID: 30229917. 6: Li QF, Lü YL, Wang P, Zhang YQ. [Selection of Priority Contaminants in a Watershed Using Risk Ranking Methodology]. Huan Jing Ke Xue. 2018 Oct 8;39(10):4472-4478. doi: 10.13227/j.hjkx.201802135. Chinese. PubMed PMID: 30229593. 7: Wang L, Xue C, Zhang Y, Li Z, Liu C, Pan X, Chen F, Liu Y. Soil aggregate-associated distribution of DDTs and HCHs in farmland and bareland soils in the Danjiangkou Reservoir Area of China. Environ Pollut. 2018 Sep 11. pii: S0269-7491(18)32241-3. doi: 10.1016/j.envpol.2018.09.019. [Epub ahead of print] PubMed PMID: 30228065. 8: Jayasinghe S, Lind L, Salihovic S, Larsson A, Lind PM. DDT and its metabolites could contribute to the aetiology of chronic kidney disease of unknown aetiology (CKDu) and more studies are a priority. Sci Total Environ. 2018 Sep 12. pii: S0048-9697(18)33558-7. doi: 10.1016/j.scitotenv.2018.09.116. [Epub ahead of print] PubMed PMID: 30227991. 9: Aplasca AC, Titus V, Ossiboff RJ, Murphy L, Seimon TA, Ingerman K, Moser WE, Calle PP, Sykes JM 4th. Health Assessment of Free-Ranging Chelonians in an Urban Section of the Bronx River, New York. J Wildl Dis. 2018 Sep 18. doi: 10.7589/2017-12-304. [Epub ahead of print] PubMed PMID: 30226800. 10: Cohn BA, Cirillo PM, La Merrill MA. Correlation of body mass index with serum DDTs predicts lower risk of breast cancer before the age of 50: prospective evidence in the Child Health and Development Studies. J Expo Sci Environ Epidemiol. 2018 Sep 17. doi: 10.1038/s41370-018-0072-7. [Epub ahead of print] PubMed PMID: 30224754. 11: Li Q, Wang M, Duan L, Qiu Y, Ma T, Chen L, Breitholtz M, Bergman Å, Zhao J, Hecker M, Wu L. Multiple biomarker responses in caged benthic gastropods Bellamya aeruginosa after in situ exposure to Taihu Lake in China. Environ Sci Eur. 2018;30(1):34. doi: 10.1186/s12302-018-0164-y. Epub 2018 Sep 11. PubMed PMID: 30221106; PubMed Central PMCID: PMC6132844. 12: Kim HS, Hur SJ. Degradation of various insecticides in cooked eggs during in vitro human digestion. Environ Pollut. 2018 Sep 4;243(Pt A):437-443. doi: 10.1016/j.envpol.2018.09.021. [Epub ahead of print] PubMed PMID: 30212798. 13: Wang M, Zhou X, Zang X, Pang Y, Chang Q, Wang C, Wang Z. Determination of pesticides residues in vegetable and fruit samples by solid-phase microextraction with a covalent organic framework as the fiber coating coupled with gas chromatography-electron capture detection. J Sep Sci. 2018 Sep 13. doi: 10.1002/jssc.201800644. [Epub ahead of print] PubMed PMID: 30211980. 14: Lawrenz M, Finsterbusch J. Detection of microscopic diffusion anisotropy in human cortical gray matter in vivo with double diffusion encoding. Magn Reson Med. 2018 Sep 11. doi: 10.1002/mrm.27451. [Epub ahead of print] PubMed PMID: 30206991. 15: Monclús L, Lopez-Bejar M, De la Puente J, Covaci A, Jaspers VLB. Can variability in corticosterone levels be related to POPs and OPEs in feathers from nestling cinereous vultures (Aegypius monachus)? Sci Total Environ. 2018 Aug 17;650(Pt 1):184-192. doi: 10.1016/j.scitotenv.2018.08.188. [Epub ahead of print] PubMed PMID: 30196218. 16: Steyn L, Hoffman J, Bouwman H, Maina AW, Maina JN. Bone density and asymmetry are not related to DDT in House Sparrows: Insights from micro-focus X-ray computed tomography. Chemosphere. 2018 Aug 25;212:734-743. doi: 10.1016/j.chemosphere.2018.08.119. [Epub ahead of print] PubMed PMID: 30179838. 17: Wolmarans NJ, Du Preez LH, Yohannes YB, Ikenaka Y, Ishizuka M, Smit NJ, Wepener V. Linking organochlorine exposure to biomarker response patterns in Anurans: a case study of Müller's clawed frog (Xenopus muelleri) from a tropical malaria vector control region. Ecotoxicology. 2018 Sep 1. doi: 10.1007/s10646-018-1972-y. [Epub ahead of print] PubMed PMID: 30173332. 18: Berghuis SA, Van Braeckel KNJA, Sauer PJJ, Bos AF. Prenatal exposure to persistent organic pollutants and cognition and motor performance in adolescence. Environ Int. 2018 Aug 29;121(Pt 1):13-22. doi: 10.1016/j.envint.2018.08.030. [Epub ahead of print] PubMed PMID: 30172231. 19: Raslan AA, Elbadry S, Darwish WS. Estimation and Human Health Risk Assessment of Organochlorine Pesticides in Raw Milk Marketed in Zagazig City, Egypt. J Toxicol. 2018 Aug 12;2018:3821797. doi: 10.1155/2018/3821797. eCollection 2018. PubMed PMID: 30158973; PubMed Central PMCID: PMC6109547. 20: Song Y, Yang L. Transgenerational impaired spermatogenesis with sperm H19 and Gtl2 hypomethylation induced by the endocrine disruptor p,p'-DDE. Toxicol Lett. 2018 Nov;297:34-41. doi: 10.1016/j.toxlet.2018.08.015. Epub 2018 Aug 25. PubMed PMID: 30153481.